Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.
|Gene Name:||chemokine (C-X-C motif) ligand 13|
|Family/Subfamily:||Intercrine , Intercrine alpha|
|Synonyms:||CXCL13, ANGIE, ANGIE2, BLC, B cell-attracting chemokine 1, BCA-1, BCA1, C-X-C motif chemokine 13, SCYB13, Small-inducible cytokine B13, B lymphocyte chemoattractant, B-cell chemoattractant, B-cell-attracting chemokine 1, B-lymphocyte chemoattractant, Blc chemoattractant, BLR1L, Chemoattractant blc, CXC chemokine BLC|
|Target Sequences:||NM_006419 NP_006410.1 O43927|
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