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BLAP75 / RMI1

RecQ mediated genome instability 1

Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.

Gene Name: RecQ mediated genome instability 1
Synonyms: RMI1, BLAP75, C9orf76, FAAP75, RP11-346I8.1, BLM-associated protein 75 kDa
Target Sequences: NM_024945 NP_079221.2 Q9H9A7

Publications (1)

1
Rhodopsin Genomic Loci DNA Nanoparticles Improve Expression and Rescue of Retinal Degeneration in a Model for Retinitis Pigmentosa. Min Zheng, Rajendra N Mitra, Ellen R Weiss, Zongchao Han. Molecular therapy : the journal of the American Society of Gene Therapy. 2020 February;28:523-535. [Full Text Article] [PubMed:31879189] [PMC:PMC7001086] Related Antibodies: LS-C324699.

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).