BIRC8 / ILP2

baculoviral IAP repeat containing 8

Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.

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Products

Antibodies (13)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (13)

Recombinant (3)

Target

BIRC8 / ILP2 (18)

Reactivity

Human (13)

Mouse (5)

Rat (4)

Application

IHC (2)

IHC-P (1)

WB (13)

ELISA (4)

ICC (2)

IF (1)

Peptide-ELISA (1)

Host

rabbit (12)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (13)

Clonality

polyclonal pc (13)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (9)

Epitope

aa2-13 (2)

aa1-236 (1)

Publications

No (18)

Tag

GST (1)

GST, N-terminus (2)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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IHC-plus™ BIRC8 / ILP2 Antibody LS-B457

(4.0) Rating

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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BIRC8 / ILP2 Antibody LS-C409127

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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BIRC8 / ILP2 Antibody (aa2-13) LS-C82962

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal (aa2-13) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, WB

Format:

Unconjugated

Price:

100 µg/$522

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BIRC8 / ILP2 Antibody LS-C24641

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$444; 100 µg/$597

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BIRC8 / ILP2 Antibody LS-C659937

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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BIRC8 / ILP2 Antibody (aa1-236) LS-C378745

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal (aa1-236) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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BIRC8 / ILP2 Antibody LS-C806806

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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BIRC8 / ILP2 Antibody (aa2-13) LS-C42941

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal (aa2-13) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

0.1 mg/$378

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BIRC8 / ILP2 Antibody LS-C308483

Antibody:

BIRC8 / ILP2 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

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BIRC8 / ILP2 Antibody (HRP) LS-C546997

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$830

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BIRC8 / ILP2 Antibody (Biotin) LS-C526891

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$830

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BIRC8 / ILP2 Antibody (FITC) LS-C536873

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$830

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BIRC8 / ILP2 Antibody (PE) LS-C655050

Antibody:

BIRC8 / ILP2 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$830

• HRP
• Biotin
• FITC
• PE

• HRP
• Biotin
• FITC
• More...
  • PE

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BIRC8 / ILP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108292

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.9 kDa

Price:

100 µg/$494

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Human BIRC8 / ILP2 Protein (Recombinant GST) (Full Length) - LS-G36125

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

53.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human BIRC8 / ILP2 Protein (Recombinant GST, N-terminus) (aa1-236) - LS-G56867

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human BIRC8 / ILP2 Protein (Recombinant GST, N-terminus) (aa127-236) - LS-G63520

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human BIRC8 / ILP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92823

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.9 kDa

Price:

20 µg/$150

Viewing 1-18 of 18 product results

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