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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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BGN / Biglycan

biglycan

BGN / Biglycan is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex.

Gene Name: biglycan
Synonyms: BGN, Bone/cartilage proteoglycan I, Biglycan, Biglycan proteoglycan, DSPG1, PG-S1, Small leucine-rich protein 1A, PGI, Bone/cartilage proteoglycan-I, SLRR1A
Target Sequences: NM_001711 NP_001702.1 P21810

Publications (2)

1
Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, Suzuki H, Mori M, Inagawa M, Ichinose S, Lotz MK, Sakai D, Masuda K, Ozaki T, Asahara H. Nature communications. 2016 7:12503. (IHC, WB, ELISA; Human) [Full Text Article] [PubMed:27527664] [PMC:PMC4990710]
2
Airn Regulates Igf2bp2 Translation in Cardiomyocytes. Hosen MR, Militello G, Weirick T, Ponomareva Y, Dassanayaka S, Moore JB 4th, Döring C, Wysoczynski M, Jones SP, Dimmeler S, Uchida S. Circulation research. 2018 May;122:1347-1353. [Full Text Article] [PubMed:29483092] [PMC:PMC5948151]

Viewing 1-25 of 81 items
BGN / Biglycan Antibody - Human Spleen, Trabecula: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse BGN / Biglycan
Mouse
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $535.00
BGN / Biglycan Antibody - Human Spleen, Trabecula: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal to Human BGN / Biglycan
Pig, Human
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $535.00
BGN / Biglycan Antibody - Human Spleen, Trabecula: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal to Human BGN / Biglycan
Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $535.00
BGN / Biglycan Antibody - Immunohistochemistry of monoclonal antibody to BGN on formalin-fixed paraffin-embedded human lung, adenosquamous cell carcinoma. [antibody concentration 1 ~ 10 ug/ml]
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Mouse Monoclonal [clone 4E1-1G7] (IgG2a,k) to Human BGN / Biglycan
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100µg   0.45mg/ml   $365.00
BGN / Biglycan Antibody - Antibody (0.1 ug/ml) staining of Rat Skin lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Goat Polyclonal to Human BGN / Biglycan
Zebrafish, Pig, Horse, Rat, Hamster, Mouse, Dog, Sheep, Bovine, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
BGN / Biglycan Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using BGN Polyclonal Antibody at dilution of 1:50.
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Rabbit Polyclonal (IgG) to Human BGN / Biglycan
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl   0.6mg/ml   $205.00; 60µl   0.6mg/ml   $235.00; 120µl   0.6mg/ml   $295.00; 200µl   0.6mg/ml   $395.00
BGN / Biglycan Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with BGN Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Rabbit Polyclonal to Human BGN / Biglycan
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
BGN / Biglycan Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using BGN Polyclonal Antibody at dilution of 1:50.
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Rabbit Polyclonal (IgG) to Human BGN / Biglycan
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20µl   0.6mg/ml   $205.00; 60µl   0.6mg/ml   $235.00; 120µl   0.6mg/ml   $295.00; 200µl   0.6mg/ml   $395.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse BGN / Biglycan
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $265.00; 200µl   0.5mg/ml   $305.00; 500µl   0.5mg/ml   $445.00; 1ml   0.5mg/ml   $545.00
Select
Rabbit Polyclonal (IgG) to Human BGN / Biglycan
Human
WB
Unconjugated
100µg   $605.00
BGN / Biglycan Antibody - BGN / Biglycan antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human BGN / Biglycan
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $385.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse BGN / Biglycan
Mouse
WB
Biotin Conjugated
200µl   0.5mg/ml   $315.00; 500µl   0.5mg/ml   $475.00; 1ml   0.5mg/ml   $590.00
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Rabbit Polyclonal (IgG) to Human BGN / Biglycan
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $405.00
BGN / Biglycan Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Rabbit Polyclonal (IgG) to Human BGN / Biglycan
Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
BGN / Biglycan Antibody - Western blot analysis of extracts of various cell lines.
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Rabbit Polyclonal (IgG) to Human BGN / Biglycan
Mouse, Rat, Human
IHC, WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $315.00; 200µl   $425.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Rat BGN / Biglycan
Rat
ICC, IP, WB
Unconjugated
100µl   1mg/ml   $275.00; 200µl   1mg/ml   $385.00; 500µl   1mg/ml   $485.00; 1ml   1mg/ml   $605.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Rat BGN / Biglycan
Rat
ICC, IP, WB
HRP Conjugated
200µl   0.5mg/ml   $365.00; 500µl   0.5mg/ml   $620.00; 1ml   0.5mg/ml   $785.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Rat BGN / Biglycan
Rat
ICC, IP, WB
Biotin Conjugated
200µl   0.5mg/ml   $335.00; 500µl   0.5mg/ml   $530.00; 1ml   0.5mg/ml   $665.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Rat BGN / Biglycan
Rat
ICC, IP, WB
FITC Conjugated
200µl   0.5mg/ml   $385.00; 500µl   0.5mg/ml   $665.00; 1ml   0.5mg/ml   $845.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Rat BGN / Biglycan
Rat
ICC, IP, WB
Cy3 Conjugated
200µl   0.1mg/ml   $485.00; 500µl   0.1mg/ml   $965.00; 1ml   0.1mg/ml   $1,200.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Rat BGN / Biglycan
Rat
ICC, IP, WB
APC Conjugated
200µl   0.1mg/ml   $405.00; 500µl   0.1mg/ml   $725.00; 1ml   0.1mg/ml   $905.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Rat BGN / Biglycan
Rat
ICC, IP, WB
PE Conjugated
200µl   0.1mg/ml   $545.00; 500µl   0.1mg/ml   $1,080.00; 1ml   0.1mg/ml   $1,350.00
BGN / Biglycan Antibody - Western blot of recombinant BGN / Biglycan.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal (IgG) to Rat BGN / Biglycan
Rat
ICC, IP, WB
APC, Cy7 Conjugated
1ml   0.1mg/ml   $1,350.00
BGN / Biglycan Antibody - Immunocytochemistry analysis of human pancreatic cancer using BGN Antibody at dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human BGN / Biglycan
Human
ELISA
Unconjugated
50µg   $285.00; 100µg   $385.00
BGN / Biglycan Antibody - Western blot analysis of extracts of various cell lines, using BGN antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5s.
Select
Rabbit Polyclonal (IgG) to Human BGN / Biglycan
Human
WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00

Viewing 1-25 of 81 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).