BEST1 / BEST / Bestrophin

bestrophin 1

BEST1 / BEST / Bestrophin is a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

BEST1 / BEST / Bestrophin (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human BEST1 / BEST / Bestrophin Protein (Recombinant GST, N-terminus) (aa361-460) - LS-G60515

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human BEST1 / BEST / Bestrophin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89237

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.5 kDa

Price:

20 µg/$215

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Human BEST1 / BEST / Bestrophin Protein (Recombinant GST) (Full Length) - LS-G30885

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

95.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human BEST1 / BEST / Bestrophin Protein (Recombinant His-GST, N-terminus) - LS-G133226

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

63.6kDa

Price:

10 µg/$269; 50 µg/$370; 200 µg/$737; 100 µg/$590; 1 mg/$1,779; 500 µg/$1,345; 5 mg/$2,736; 2 mg/$1,959

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Human BEST1 / BEST / Bestrophin Protein (Recombinant His) - LS-G2814

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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BEST1 / BEST / Bestrophin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116819

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.5 kDa

Price:

100 µg/$710

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Human BEST1 / BEST / Bestrophin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71225

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.5 kDa

Price:

20 µg/$1,107

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