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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BECN1 / Beclin-1

beclin 1, autophagy related

Beclin 1 is a coiled coil protein that interacts with prototypic cellular antiapoptotic gene Bcl2. Beclin 1 is widely expressed with highest levels reported in skeletal muscle. Three alternativaly spliced isoforms have been identified. Allelic deletion of beclin 1 results in a wide variety of cancers including breast cancer.

Gene Name: beclin 1, autophagy related
Synonyms: BECN1, ATG6, Beclin 1, Beclin 1, autophagy related, Beclin1, GT197, Protein GT197, VPS30, Beclin-1
Target Sequences: NM_003766 NP_003757.1 Q14457

Publications (32)

1
A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. Park KJ, Lee SH, Kim TI, Lee HW, Lee CH, Kim EH, Jang JY, Choi KS, Kwon MH, Kim YS. Cancer research. 2007 67:7327-34. (WB, IP; Human) [PubMed:17671202]
2
Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus. Wang Y, Singh R, Massey AC, Kane SS, Kaushik S, Grant T, Xiang Y, Cuervo AM, Czaja MJ. The Journal of biological chemistry. 2008 283:4766-77. (ICC, WB; Mouse) [PubMed:18073215] [PMC:PMC2754125]
3
Early cellular changes after blockage of chaperone-mediated autophagy. Massey AC, Follenzi A, Kiffin R, Zhang C, Cuervo AM. Autophagy. 2008 4:442-56. (WB; Mouse) [PubMed:18253088]
4
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, Gonzalez FJ, Semenza GL. The Journal of biological chemistry. 2008 283:10892-903. (WB; Mouse, Human) [PubMed:18281291] [PMC:PMC2447655]
5
Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. Gulati P, Gaspers LD, Dann SG, Joaquin M, Nobukuni T, Natt F, Kozma SC, Thomas AP, Thomas G. Cell metabolism. 2008 7:456-65. (WB; Human) [PubMed:18460336] [PMC:PMC2587347]
6
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy. Pattingre S, Bauvy C, Carpentier S, Levade T, Levine B, Codogno P. The Journal of biological chemistry. 2009 284:2719-28. (WB; Human) [PubMed:19029119] [PMC:PMC2631952]
7
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Bellot G, Garcia-Medina R, Gounon P, Chiche J, Roux D, Pouyssgur J, Mazure NM. Molecular and cellular biology. 2009 29:2570-81. [PubMed:19273585] [PMC:PMC2682037]
8
Effect of autophagy on multiple myeloma cell viability. Hoang B, Benavides A, Shi Y, Frost P, Lichtenstein A. Molecular cancer therapeutics. 2009 8:1974-84. [PubMed:19509276]
9
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. Kyei GB, Dinkins C, Davis AS, Roberts E, Singh SB, Dong C, Wu L, Kominami E, Ueno T, Yamamoto A, Federico M, Panganiban A, Vergne I, Deretic V. The Journal of cell biology. 2009 186:255-68. [PubMed:19635843] [PMC:PMC2717652]
10
Inhibition of autophagy induced by overexpression of mda-7/interleukin-24 strongly augments the antileukemia activity in vitro and in vivo. Yang C, Tong Y, Ni W, Liu J, Xu W, Li L, Liu X, Meng H, Qian W. Cancer gene therapy. 2010 17:109-19. (IP) [PubMed:19730452]
11
Substance P inhibits natural killer cell cytotoxicity through the neurokinin-1 receptor. Monaco-Shawver L, Schwartz L, Tuluc F, Guo CJ, Lai JP, Gunnam SM, Kilpatrick LE, Banerjee PP, Douglas SD, Orange JS. Journal of leukocyte biology. 2011 89:113-25. [PubMed:20940324] [PMC:PMC3004520]
12
Hypoxia-inducible factor-1 (HIF-1) and autophagy in polycystic kidney disease (PKD). Belibi F, Zafar I, Ravichandran K, Segvic AB, Jani A, Ljubanovic DG, Edelstein CL. American journal of physiology. Renal physiology. 2011 300:F1235-43. (ICC, WB, IHC-Fr; Mouse, Rat) [PubMed:21270095] [PMC:PMC3094047]
13
Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy. Cheng HC, Kim SR, Oo TF, Kareva T, Yarygina O, Rzhetskaya M, Wang C, During M, Talloczy Z, Tanaka K, Komatsu M, Kobayashi K, Okano H, Kholodilov N, Burke RE. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 31:2125-35. [PubMed:21307249] [PMC:PMC3075005]
14
Activation of autophagy in mesenchymal stem cells provides tumor stromal support. Sanchez CG, Penfornis P, Oskowitz AZ, Boonjindasup AG, Cai DZ, Dhule SS, Rowan BG, Kelekar A, Krause DS, Pochampally RR. Carcinogenesis. 2011 32:964-72. [PubMed:21317300] [PMC:PMC3128555]
15
Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival. Elgendy M, Sheridan C, Brumatti G, Martin SJ. Molecular cell. 2011 42:23-35. (WB; Human) [PubMed:21353614]
16
Presenilin is necessary for efficient proteolysis through the autophagy-lysosome system in a -secretase-independent manner. Neely KM, Green KN, LaFerla FM. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 31:2781-91. (WB; Mouse) [PubMed:21414900] [PMC:PMC3064964]
17
Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity. Dash R, Azab B, Quinn BA, Shen X, Wang XY, Das SK, Rahmani M, Wei J, Hedvat M, Dent P, Dmitriev IP, Curiel DT, Grant S, Wu B, Stebbins JL, Pellecchia M, Reed JC, Sarkar D, Fisher PB. Proceedings of the National Academy of Sciences of the United States of America. 2011 108:8785-90. (WB, IP; Human) [PubMed:21555592] [PMC:PMC3102401]
18
Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth. Chiavarina B, Whitaker-Menezes D, Martinez-Outschoorn UE, Witkiewicz AK, Birbe R, Howell A, Pestell RG, Smith J, Daniel R, Sotgia F, Lisanti MP. Cancer biology & therapy. 2011 12:1101-13. (WB; Human) [PubMed:22236875] [PMC:PMC3335944]
19
Basal autophagy decreased during the differentiation of human adult mesenchymal stem cells. Oliver L, Hue E, Priault M, Vallette FM. Stem cells and development. 2012 21:2779-88. [PubMed:22519885]
20
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. Dehay B, Ramirez A, Martinez-Vicente M, Perier C, Canron MH, Doudnikoff E, Vital A, Vila M, Klein C, Bezard E. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:9611-6. (IHC, WB; Human) [PubMed:22647602] [PMC:PMC3386132]
21
Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production. Capparelli C, Guido C, Whitaker-Menezes D, Bonuccelli G, Balliet R, Pestell TG, Goldberg AF, Pestell RG, Howell A, Sneddon S, Birbe R, Tsirigos A, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Cell cycle (Georgetown, Tex.). 2012 11:2285-302. (WB; Human) [PubMed:22684298] [PMC:PMC3383590]
22
CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth. Capparelli C, Whitaker-Menezes D, Guido C, Balliet R, Pestell TG, Howell A, Sneddon S, Pestell RG, Martinez-Outschoorn U, Lisanti MP, Sotgia F. Cell cycle (Georgetown, Tex.). 2012 11:2272-84. (WB; Human) [PubMed:22684333] [PMC:PMC3383589]
23
Metabolic reprogramming of cancer-associated fibroblasts by TGF- drives tumor growth: connecting TGF- signaling with "Warburg-like" cancer metabolism and L-lactate production. Guido C, Whitaker-Menezes D, Capparelli C, Balliet R, Lin Z, Pestell RG, Howell A, Aquila S, And S, Martinez-Outschoorn U, Sotgia F, Lisanti MP. Cell cycle (Georgetown, Tex.). 2012 11:3019-35. (WB; Human) [PubMed:22874531] [PMC:PMC3442913]
24
Tryptophan depletion and the kinase GCN2 mediate IFN--induced autophagy. Fougeray S, Mami I, Bertho G, Beaune P, Thervet E, Pallet N. Journal of immunology (Baltimore, Md. : 1950). 2012 189:2954-64. (WB; Human) [PubMed:22896630]
25
Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth. Carito V, Bonuccelli G, Martinez-Outschoorn UE, Whitaker-Menezes D, Caroleo MC, Cione E, Howell A, Pestell RG, Lisanti MP, Sotgia F. Cell cycle (Georgetown, Tex.). 2012 11:3403-14. (WB; Human) [PubMed:22918248] [PMC:PMC3466551]
26
CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis. Capparelli C, Chiavarina B, Whitaker-Menezes D, Pestell TG, Pestell RG, Hulit J, And S, Howell A, Martinez-Outschoorn UE, Sotgia F, Lisanti MP. Cell cycle (Georgetown, Tex.). 2012 11:3599-610. (WB; Human) [PubMed:22935696] [PMC:PMC3478311]
27
8-Amino-adenosine activates p53-independent cell death of metastatic breast cancers. Polotskaia A, Hoffman S, Krett NL, Shanmugam M, Rosen ST, Bargonetti J. Molecular cancer therapeutics. 2012 11:2495-504. (WB; Human) [PubMed:22973058] [PMC:PMC3535282]
28
Beclin-1 expression is a significant predictor of survival in patients with lymph node-positive gastric cancer. Geng QR, Xu DZ, He LJ, Lu JB, Zhou ZW, Zhan YQ, Lu Y. PloS one. 2012 7:e45968. (IHC, WB; Human) [PubMed:23029344] [PMC:PMC3459952]
29
Ketone body utilization drives tumor growth and metastasis. Martinez-Outschoorn UE, Lin Z, Whitaker-Menezes D, Howell A, Sotgia F, Lisanti MP. Cell cycle (Georgetown, Tex.). 2012 11:3964-71. (WB; Human) [PubMed:23082722] [PMC:PMC3507492]
30
RNase L induces autophagy via c-Jun N-terminal kinase and double-stranded RNA-dependent protein kinase signaling pathways. Siddiqui MA, Malathi K. The Journal of biological chemistry. 2012 287:43651-64. (IP; Human) [PubMed:23109342] [PMC:PMC3527951]
31
Molecular determinants of selective clearance of protein inclusions by autophagy. Wong E, Bejarano E, Rakshit M, Lee K, Hanson HH, Zaarur N, Phillips GR, Sherman MY, Cuervo AM. Nature communications. 2012 3:1240. (ICC; Human) [PubMed:23212369] [PMC:PMC3526956]
32
Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7g. Messam CA, Hou J, Berman JW, Major EO. International journal of cardiology. 2013 (ICC, IHC; Mouse) [PubMed:23305858]
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Target
BECN1 / Beclin-1 (170)
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Human (160)
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rabbit (143)
mouse (27)
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monoclonal mc (27)
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PE Conjugated (11)
Unconjugated (71)
Epitope
aa1-273 (10)
aa100-123 (8)
aa210-239 (8)
aa52-78 (8)
aa95-132 (8)
pSer64 (8)
Internal (7)
T119 (7)
N-Terminus (6)
aa210-259 (4)
aa234-264 (4)
aa45-94 (4)
aa49-79 (4)
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aa1-100 (3)
Arg238 (1)
Ser249 (1)
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aa1-354 (1)
aa1-50 (1)
aa12-239 (1)
aa181-210 (1)
aa222-237 (1)
aa388-421 (1)
aa50-100 (1)
aa69-73 (1)
pSer234 (1)
pSer295 (1)
Publications
No (170)
Showing 1-25 of 170 results

BECN1 / Beclin-1 Antibody (C-Terminus) IHC-plus™ LS-B3202
Rabbit Polyclonal (IgG) to Human BECN1 / Beclin-1
Mouse, Human
ELISA ICC IF IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-BECN1 / Beclin-1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-BECN1 / Beclin-1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-BECN1 / Beclin-1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-BECN1 / Beclin-1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

BECN1 / Beclin-1 Antibody (N-Terminus) IHC-plus™ LS-B3203
Rabbit Polyclonal (IgG) to Human BECN1 / Beclin-1
Mouse, Rat, Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-BECN1 / Beclin-1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-BECN1 / Beclin-1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-BECN1 / Beclin-1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-BECN1 / Beclin-1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

BECN1 / Beclin-1 Antibody (clone 1F1) LS-C172820
Mouse Monoclonal [clone 1F1] (IgG2a) to Human BECN1 / Beclin-1
Dog, Rat, Human
Flo IF IHC IHC-P WB
Unconjugated
100µl 0.35mg/ml  $335.00
IHC of paraffin-embedded Human liver tissue using anti-BECN1 mouse monoclonal antibody.
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.
IHC of paraffin-embedded Human liver tissue using anti-BECN1 mouse monoclonal antibody.
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.

BECN1 / Beclin-1 Antibody (clone 1B7) IHC-plus™ LS-B7758
Mouse Monoclonal [clone 1B7] to Human BECN1 / Beclin-1
Human
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $425.00
Anti-Beclin 1 antibody IHC of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-Beclin 1 antibody IHC of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BECN1 / Beclin-1 Antibody (clone 4H10) LS-C83860
Mouse Monoclonal [clone 4H10] (IgG1,k) to Human BECN1 / Beclin-1
Mouse, Human
IHC WB
Unconjugated
100µl 1mg/ml  $335.00
Staining of Beclin 1 in mouse lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of Beclin 1 in mouse lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BECN1 / Beclin-1 Antibody IHC-plus™ LS-B510
Rabbit Polyclonal to Human BECN1 / Beclin-1
Mouse, Human
IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-BECN1 / Beclin-1 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 25 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-BECN1 / Beclin-1 antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 25 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BECN1 / Beclin-1 Antibody (aa95-132) LS-C319823
Rabbit Polyclonal (IgG) to Human BECN1 / Beclin-1
Mouse, Human
ELISA Flo IHC WB
Unconjugated
200µl  $530.00

BECN1 / Beclin-1 Antibody (aa95-132, FITC) LS-C208109
Rabbit Polyclonal (IgG) to Human BECN1 / Beclin-1
Mouse, Human
ELISA Flo IHC WB
FITC Conjugated
200µl 0.5mg/ml  $680.00

BECN1 / Beclin-1 Antibody (Internal) LS-C141882
Rabbit Polyclonal to Human BECN1 / Beclin-1
Mouse, Bovine, Rat, Pig, Primate, Human
IHC IHC-P WB
Unconjugated
50µl 0.2mg/ml  $335.00
Beclin1 Antibody - Staining of breast carcinoma.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Beclin1 Antibody - Staining of normal breast tissue.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Beclin1 Antibody - Staining of breast carcinoma.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Beclin1 Antibody - Staining of normal breast tissue.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

BECN1 / Beclin-1 Antibody (clone 3F3) LS-C172744
Mouse Monoclonal [clone 3F3] (IgG1) to Human BECN1 / Beclin-1
Rat, Human, Monkey
Flo IF IHC IHC-P WB
Unconjugated
100µl 0.78mg/ml  $335.00
IHC of paraffin-embedded Human Kidney tissue using anti-BECN1 mouse monoclonal antibody.
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.
IHC of paraffin-embedded Human Kidney tissue using anti-BECN1 mouse monoclonal antibody.
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.

BECN1 / Beclin-1 Antibody (clone 3H8) LS-C337286
Mouse Monoclonal [clone 3H8] (IgG2a) to Human BECN1 / Beclin-1
Rat, Human, Monkey
Flo IF IHC IHC-P WB
Unconjugated
100µl 0.55mg/ml  $335.00
IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-BECN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
IHC of paraffin-embedded Human Kidney tissue using anti-BECN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-BECN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
IHC of paraffin-embedded Human Kidney tissue using anti-BECN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

BECN1 / Beclin-1 Antibody (aa95-132) LS-C156791
Rabbit Polyclonal to Human BECN1 / Beclin-1
Mouse, Human
Flo IHC IHC-P WB
Unconjugated
400µl  $305.00
Beclin1-BH3 Domain Antibody IHC of formalin-fixed and paraffin-embedded mouse brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the Beclin1-BH3 Domain Antibody for immunohistochemistry.
Western blot of Beclin1-BH3 Domain Antibody in mouse stomach tissue lysates (35 ug/lane). BECN1 (arrow) was detected using the purified antibody.
Beclin1-BH3 Domain Antibody IHC of formalin-fixed and paraffin-embedded mouse brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the Beclin1-BH3 Domain Antibody for immunohistochemistry.
Western blot of Beclin1-BH3 Domain Antibody in mouse stomach tissue lysates (35 ug/lane). BECN1 (arrow) was detected using the purified antibody.

BECN1 / Beclin-1 Antibody (clone 3C3) LS-C172805
Mouse Monoclonal [clone 3C3] (IgG1) to Human BECN1 / Beclin-1
Dog, Rat, Human, Monkey
Flo IF IHC IHC-P WB
Unconjugated
100µl 0.37mg/ml  $345.00
IHC of paraffin-embedded Human pancreas tissue using anti-BECN1 mouse monoclonal antibody.
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.
IHC of paraffin-embedded Human pancreas tissue using anti-BECN1 mouse monoclonal antibody.
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.

BECN1 / Beclin-1 Antibody (clone 1E1) LS-C172840
Mouse Monoclonal [clone 1E1] (IgG1) to Human BECN1 / Beclin-1
Human
Flo IF IHC IHC-P WB
Unconjugated
100µl 0.37mg/ml  $335.00
IHC of paraffin-embedded Human pancreas tissue using anti-BECN1 mouse monoclonal antibody.
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.
IHC of paraffin-embedded Human pancreas tissue using anti-BECN1 mouse monoclonal antibody.
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.

BECN1 / Beclin-1 Antibody (aa388-421) LS-C356581
Rabbit Polyclonal to Zebrafish BECN1 / Beclin-1
Zebrafish
Peptide-ELISA WB
Unconjugated
400µl  $305.00
All lanes : Anti-becn1 Antibody at 1:2000 dilution Lane 1: Zebrafish lysates Lane 2: ZF4 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
All lanes : Anti-becn1 Antibody at 1:2000 dilution Lane 1: Zebrafish lysates Lane 2: ZF4 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

BECN1 / Beclin-1 Antibody (clone 2A4) LS-C169332
Mouse Monoclonal [clone 2A4] (IgG1) to Human BECN1 / Beclin-1
Human
ELISA Flo IHC WB
Unconjugated
100µl  $365.00
IHC of paraffin-embedded breast cancer tissues (left) and liver cancer tissues (right) using BECN1 mouse monoclonal antibody with DAB staining.
Western blot using BECN1 mouse monoclonal antibody against HeLa (1), A431 (2), MCF-7 (3), RAJI (4), Jurkat (5) and SKBR-3 (6) cell lysate.
IHC of paraffin-embedded breast cancer tissues (left) and liver cancer tissues (right) using BECN1 mouse monoclonal antibody with DAB staining.
Western blot using BECN1 mouse monoclonal antibody against HeLa (1), A431 (2), MCF-7 (3), RAJI (4), Jurkat (5) and SKBR-3 (6) cell lysate.

BECN1 / Beclin-1 Antibody (aa210-259) LS-C117076
Rabbit Polyclonal to Human BECN1 / Beclin-1
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
BECN1 / Beclin-1 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
BECN1 / Beclin-1 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

BECN1 / Beclin-1 Antibody LS-C500779
Rabbit Polyclonal (IgG) to Human BECN1 / Beclin-1
Mouse, Human
ELISA IF IHC WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human colon cancer using BECN1 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using BECN1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human colon cancer using BECN1 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using BECN1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

BECN1 / Beclin-1 Antibody LS-C156793
Mouse Monoclonal (IgM) to Human BECN1 / Beclin-1
Human
IF IHC IHC-P WB
Unconjugated
100µl  $305.00
Formalin-fixed and paraffin-embedded human brain with BECN1 Monoclonal Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Immunofluorescence of BECN1 Monoclonal Antibody with paraffin-embedded human brain tissue.0.05 mg/ml primary antibody was followed by PE-conjugated goat anti-mouse lgG (whole molecule). PE emits orange fluorescence.
Formalin-fixed and paraffin-embedded human brain with BECN1 Monoclonal Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Immunofluorescence of BECN1 Monoclonal Antibody with paraffin-embedded human brain tissue.0.05 mg/ml primary antibody was followed by PE-conjugated goat anti-mouse lgG (whole molecule). PE emits orange fluorescence.

BECN1 / Beclin-1 Antibody (aa210-239) LS-C156787
Rabbit Polyclonal to Human BECN1 / Beclin-1
Mouse, Human
Flo IHC IHC-P WB
Unconjugated
400µl  $305.00
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
The anti-BECN1 antibody is used in Western blot to detect BECN1 in, from left to right, A2058, HeLa, mouse brain, Y79, and HL60 tissue lysates. BECN1(arrow) was detected using the purified antibody.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
The anti-BECN1 antibody is used in Western blot to detect BECN1 in, from left to right, A2058, HeLa, mouse brain, Y79, and HL60 tissue lysates. BECN1(arrow) was detected using the purified antibody.

BECN1 / Beclin-1 Antibody (clone 2C5) LS-C172804
Mouse Monoclonal [clone 2C5] (IgG2a) to Human BECN1 / Beclin-1
Human
Flo IF WB
Unconjugated
100µl  $335.00
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.
Immunofluorescent staining of HeLa cells using anti-BECN1 mouse monoclonal antibody.
Anti-BECN1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BECN1.
Immunofluorescent staining of HeLa cells using anti-BECN1 mouse monoclonal antibody.

BECN1 / Beclin-1 Antibody LS-C659693
Rabbit Polyclonal (IgG) to Human BECN1 / Beclin-1
Human
ELISA IF IHC IP WB
Unconjugated
100µg  $435.00

BECN1 / Beclin-1 Antibody (aa210-239) LS-C319821
Rabbit Polyclonal (IgG) to Human BECN1 / Beclin-1
Mouse, Human
ELISA Flo IHC WB
Unconjugated
200µl  $530.00

BECN1 / Beclin-1 Antibody (clone AT45E8) LS-C755406
Mouse Monoclonal [clone AT45E8] (IgG2b,k) to Human BECN1 / Beclin-1
Human
ELISA Flo ICC WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $315.00
ICC/IF analysis of BECN1 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human BECN1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
The Recombinant Human BECN1 (10ng) and Cell lysates were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human BECN1 antibody (1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: Recombinant Human BECN1 Lane 2.: Balb/3T3 cell lysate The Cell lysates (10ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human BECN1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: 293T cell lysate Lane 2.: BECN1 Transfected 293T cell lysate
ICC/IF analysis of BECN1 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human BECN1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
The Recombinant Human BECN1 (10ng) and Cell lysates were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human BECN1 antibody (1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: Recombinant Human BECN1 Lane 2.: Balb/3T3 cell lysate The Cell lysates (10ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human BECN1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: 293T cell lysate Lane 2.: BECN1 Transfected 293T cell lysate

BECN1 / Beclin-1 Antibody (N-Terminus) IHC-plus™ LS-B12738
Rabbit Polyclonal to Human BECN1 / Beclin-1
Human, Monkey
IHC IHC-P WB
Unconjugated
50µg  $485.00
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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