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BDP1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BDP1 is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription.
| Gene Name: | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB |
| Synonyms: | BDP1, HSA238520, KIAA1689, KIAA1241, TFIIIB'', TFIIIB90, TFIIIB150, TAF3B1, TFIIIB, Transcription factor IIIB 150, TFC5, TFNR |
| Target Sequences: | A6H8Y1 A6H8Y1 |
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