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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BDNF

brain-derived neurotrophic factor

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Gene Name: brain-derived neurotrophic factor
Family/Subfamily: NGF Beta , not assigned-NGF Beta
Synonyms: BDNF, ANON2, Abrineurin, BULN2, Neurotrophin
Target Sequences: NM_001709 NP_001700.2 P23560

Publications (3)

1
Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats. McCarthy CA, Vinh A, Miller AA, Hallberg A, Alterman M, Callaway JK, Widdop RE. PloS one. 2014 9:e95762. (Flo; Rat) [Full Text Article] [PubMed:24752645] [PMC:PMC3994132] Related Antibodies: LS-B3815.
2
Antidepressant-Like Effects of Acupuncture-Insights From DNA Methylation and Histone Modifications of Brain-Derived Neurotrophic Factor. Jiang H, Zhang X, Lu J, Meng H, Sun Y, Yang X, Zhao B, Bao T. Frontiers in psychiatry. 2018 March;9:102. (Human) [Full Text Article] [PubMed:29636708] [PMC:PMC5880910] Related Antibodies: LS-C343943.
3
TRKB tyrosine kinase receptor is a potential therapeutic target for poorly differentiated oral squamous cell carcinoma. Moriwaki K, Ayani Y, Kuwabara H, Terada T, Kawata R, Asahi M. Oncotarget. 2018 May;9:25225-25243. (Human) [Full Text Article] [PubMed:29861866] [PMC:PMC5982746]

Filtered by: None
Type
Over-Expression Cell Culture Supernatant (2)
Over-Expression Lysate (40)
Recombinant (34)
Target
BDNF (76)
Tag
GST (5)
GST,N-terminus (2)
His (7)
His + GST (2)
His + SUMO (1)
His, C-Terminal (1)
His, N-Terminal (8)
Myc + DDK (37)
Species
Chicken (1)
Dog (1)
Guinea pig (1)
Horse (1)
Human (43)
Mouse (2)
Pig (3)
Rabbit (1)
Rat (2)
Source
293F Cells (1)
293T Cells (17)
CHO Cells (1)
E. coli (29)
HEK 293 Cells (24)
Sf9 Cells (1)
Wheat Germ Extract (2)
Purification
Purified (29)
Supernatant (2)
Low Endotoxin Level
Low endotoxin level (12)
Biologically Active
Biologically active (9)
Animal-free
Animal-free (2)
Publications
No (76)
Showing 1-25 of 76 results

Human BDNF Protein (Recombinant) - LS-G441
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
27.0 kDa
2µg  $215.00; 10µg  $285.00

Human BDNF Protein (Recombinant) - LS-G3616
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2µg  $225.00; 10µg  $295.00

Rat BDNF Protein (Recombinant His) (aa117-248) - LS-G11268
E. coli
His
16.6 kDa
10µg  $295.00; 50µg  $495.00; 100µg  $695.00; 200µg  $1,005.00; 1mg  $2,580.00; 500µg  $1,140.00
Recombinant Brain Derived Neurotrophic Factor By SDS-PAGE

Chicken BDNF Protein (Recombinant His) (aa134-238) - LS-G11263
E. coli
His
13.5 kDa
10µg  $325.00; 50µg  $620.00; 100µg  $845.00; 200µg  $1,230.00; 1mg  $3,150.00; 500µg  $1,395.00
Recombinant Brain Derived Neurotrophic Factor By SDS-PAGE

Dog BDNF Protein (Recombinant His, N-Terminal) (aa128-243) - LS-G11257
E. coli
His, N-Terminal
14.7 kDa
10µg  $305.00; 50µg  $545.00; 100µg  $740.00; 200µg  $1,080.00; 1mg  $2,805.00; 500µg  $1,245.00
Recombinant Brain Derived Neurotrophic Factor By SDS-PAGE

Rat BDNF Protein (Recombinant His) (aa136-243) - LS-G22699
E. coli
His
16.4 kD
1000µg  $1,845.00; 500µg  $1,155.00; 200µg  $695.00; 50µg  $325.00; 10µg  $275.00; 100µg  $445.00

Human BDNF Protein (Recombinant GST) (aa137-237) - LS-G22285
E. coli
GST
38.9 kD
1000µg  $1,245.00; 500µg  $785.00; 200µg  $475.00; 50µg  $275.00; 10µg  $235.00; 100µg  $355.00

Human BDNF Protein (Recombinant GST) (aa137-237) - LS-G22286
E. coli
GST
38.9 kD
1000µg  $1,245.00; 500µg  $785.00; 200µg  $475.00; 50µg  $275.00; 10µg  $235.00; 100µg  $355.00

Human BDNF Protein (Recombinant) - LS-G16603
E. coli
None
52.0 kDa
2µg  $195.00; 10µg  $255.00; 1mg  $5,460.00

BDNF Protein (Over-Expression Lysate GST,N-terminus) - LS-G41578
E. coli
GST,N-terminus
47 kDa
200µg  $315.00

BDNF Protein (Over-Expression Lysate GST,N-terminus) - LS-G41579
E. coli
GST,N-terminus
40 kDa
200µg  $315.00

Human BDNF Protein (Recombinant His + SUMO) (aa129-247) - LS-G20524
E. coli
His + SUMO
29.5 kD
1000µg  $1,245.00; 500µg  $785.00; 200µg  $475.00; 50µg  $275.00; 10µg  $235.00; 100µg  $355.00

Human BDNF Protein (Recombinant) - LS-G37761
None
Biologically active
27.0 kD
10µg  $405.00

Human BDNF Protein (Recombinant) - LS-G4204
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein.
27.0 kDa
50µg  $830.00; 250µg  $2,625.00; 1mg  $7,125.00; 10µg  $365.00

Human BDNF Protein (Recombinant) - LS-G16744
E. coli
None
Biologically active
26.984 kDa
2µg  $195.00; 10µg  $255.00; 1mg  $4,950.00

Human BDNF Protein (Recombinant) - LS-G4374
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
~52 kDa
50µg  $710.00; 1mg  $5,700.00; 10µg  $335.00

Human BDNF Protein (Recombinant His, N-Terminal) (His129-Arg247) - LS-G132895
293F Cells
His, N-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
25kDa
10µg  $445.00; 50µg  $1,080.00; 200µg  $2,160.00; 100µg  $1,725.00; 1mg  $6,480.00; 500µg  $2,880.00
Eukaryotic Brain Derived Neurotrophic Factor (BDNF) by SDS-PAGE

Human BDNF Protein (Recombinant His, N-Terminal) (Pro20-Arg252) - LS-G132653
E. coli
His, N-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
27.4kDa
10µg  $285.00; 50µg  $485.00; 200µg  $965.00; 100µg  $770.00; 1mg  $2,910.00; 500µg  $1,290.00
Recombinant Brain Derived Neurotrophic Factor (BDNF) by SDS-PAGE

Human BDNF Protein (Recombinant GST) (Full Length) - LS-G27622
Wheat Germ Extract
GST
52.91 kDa
2µg  $385.00
12.5% SDS-PAGE of human BDNF stained with Coomassie Blue

Human BDNF Protein (Recombinant GST) (Full Length) - LS-G27623
Wheat Germ Extract
GST
55.3 kDa
2µg  $385.00
12.5% SDS-PAGE of human BDNF stained with Coomassie Blue

Rabbit BDNF Protein (Recombinant His) (aa16-183) - LS-G11267
E. coli
His
20.0 kDa
10µg  $305.00; 50µg  $545.00; 100µg  $740.00; 200µg  $1,080.00; 1mg  $2,805.00; 500µg  $1,245.00
Recombinant Brain Derived Neurotrophic Factor By SDS-PAGE

Horse BDNF Protein (Recombinant His) (aa128-247) - LS-G11261
E. coli
His
15.2 kDa
10µg  $315.00; 50µg  $590.00; 100µg  $800.00; 200µg  $1,170.00; 1mg  $3,015.00; 500µg  $1,335.00
Recombinant Brain Derived Neurotrophic Factor By SDS-PAGE

Guinea pig BDNF Protein (Recombinant His + GST) (aa147-249) - LS-G11262
E. coli
His + GST
44.1 kDa
50µg  $515.00; 10µg  $295.00; 200µg  $1,020.00; 100µg  $710.00; 1mg  $2,640.00; 500µg  $1,170.00
Recombinant Brain Derived Neurotrophic Factor By SDS-PAGE

Pig BDNF Protein (Recombinant His) (aa20-252) - LS-G11264
E. coli
His
27.7 kDa
10µg  $315.00; 50µg  $560.00; 100µg  $770.00; 200µg  $1,125.00; 1mg  $2,910.00; 500µg  $1,290.00
Recombinant Brain Derived Neurotrophic Factor By SDS-PAGE

Human BDNF Protein (Recombinant GST) (aa129-247) - LS-G11265
E. coli
GST
40.0 kDa
10µg  $385.00; 50µg  $845.00; 100µg  $1,140.00; 200µg  $1,680.00; 1mg  $4,320.00; 500µg  $1,920.00
Recombinant Brain Derived Neurotrophic Factor By SDS-PAGE
Showing 1-25 of 76 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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