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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BDNF

brain-derived neurotrophic factor

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Gene Name: brain-derived neurotrophic factor
Family/Subfamily: NGF Beta , not assigned-NGF Beta
Synonyms: BDNF, ANON2, Abrineurin, BULN2, Neurotrophin
Target Sequences: NM_001709 NP_001700.2 P23560

Publications (3)

1
Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats. McCarthy CA, Vinh A, Miller AA, Hallberg A, Alterman M, Callaway JK, Widdop RE. PloS one. 2014 9:e95762. (Flo; Rat) [Full Text Article] [PubMed:24752645] [PMC:PMC3994132] Related Antibodies: LS-B3815.
2
Antidepressant-Like Effects of Acupuncture-Insights From DNA Methylation and Histone Modifications of Brain-Derived Neurotrophic Factor. Jiang H, Zhang X, Lu J, Meng H, Sun Y, Yang X, Zhao B, Bao T. Frontiers in psychiatry. 2018 March;9:102. (Human) [Full Text Article] [PubMed:29636708] [PMC:PMC5880910] Related Antibodies: LS-C343943.
3
TRKB tyrosine kinase receptor is a potential therapeutic target for poorly differentiated oral squamous cell carcinoma. Moriwaki K, Ayani Y, Kuwabara H, Terada T, Kawata R, Asahi M. Oncotarget. 2018 May;9:25225-25243. (Human) [Full Text Article] [PubMed:29861866] [PMC:PMC5982746]

Filtered by: None
Type
Over-Expression Lysate (40)
Recombinant (36)
Target
BDNF (76)
Tag
GST (5)
GST,N-terminus (2)
His (7)
His + GST (2)
His + SUMO (1)
His, C-Terminal (1)
His, N-Terminal (8)
Myc + DDK (37)
Species
Chicken (1)
Dog (1)
Guinea pig (1)
Horse (1)
Human (41)
Mouse (2)
Pig (1)
Rabbit (1)
Rat (2)
Source
293F Cells (1)
293T Cells (17)
CHO Cells (1)
E. coli (29)
HEK 293 Cells (20)
Human (2)
Pig (2)
Sf9 Cells (1)
Wheat Germ Extract (2)
Purification
Purified (29)
Low Endotoxin Level
Low endotoxin level (12)
Biologically Active
Biologically active (9)
Animal-free
Animal-free (2)
Showing 1-25 of 76 results

Rat BDNF Protein (Recombinant His) (aa117-248) - LS-G11268
E. coli
His
16.6 kDa
10µg  $295.00; 50µg  $495.00; 100µg  $695.00; 200µg  $1,005.00; 1mg  $2,580.00
Recombinant Brain Derived Neurotrophic Factor By SDS-PAGE

Human BDNF Protein (Recombinant) - LS-G441
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
27.0 kDa
2µg  $215.00; 10µg  $285.00

Human BDNF Protein (Recombinant His) - LS-G3218
E. coli
His
100µg 1mg/ml  $315.00; 0.5mg 1mg/ml  $695.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human BDNF Protein (Recombinant) - LS-G55823
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
27.2 kDa
2µg  $205.00; 100µg  $725.00; 10µg  $285.00; 1mg  $5,940.00; 500µg  $3,555.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

BDNF Protein (Over-Expression Lysate GST,N-terminus) - LS-G41578
E. coli
GST,N-terminus
47 kDa
200µg  $315.00

BDNF Protein (Over-Expression Lysate GST,N-terminus) - LS-G41579
E. coli
GST,N-terminus
40 kDa
200µg  $315.00

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G102410
HEK 293 Cells
Myc + DDK
25.7 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G102421
HEK 293 Cells
Myc + DDK
25.7 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126186
HEK 293 Cells
Myc + DDK
27.85 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126187
HEK 293 Cells
Myc + DDK
27.85 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126188
HEK 293 Cells
Myc + DDK
27.85 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126190
HEK 293 Cells
Myc + DDK
31.12 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126191
HEK 293 Cells
Myc + DDK
36.9 kDa
100µg  $345.00

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126193
HEK 293 Cells
Myc + DDK
27.85 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126192
HEK 293 Cells
Myc + DDK
27.85 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126194
HEK 293 Cells
Myc + DDK
27.85 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126196
HEK 293 Cells
Myc + DDK
25.7 kDa
100µg  $345.00

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126195
HEK 293 Cells
Myc + DDK
27.85 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126197
HEK 293 Cells
Myc + DDK
27.85 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

BDNF Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G126189
HEK 293 Cells
Myc + DDK
27.85 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Rat BDNF Protein (Recombinant His) (aa136-243) - LS-G22699
E. coli
His
16.4 kD
1000µg  $1,845.00; 500µg  $1,155.00; 200µg  $695.00; 50µg  $325.00; 10µg  $275.00; 100µg  $445.00

Human BDNF Protein (Recombinant) - LS-G23497
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
27.2 kDa
100µg  $650.00; 10µg  $275.00; 1mg  $5,400.00; 2µg  $205.00; 500µg  $3,240.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Proliferation Image

Human BDNF Protein (Recombinant) - LS-G27141
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
12-14 kDa (SDS-PAGE)
5µg  $215.00; 25µg  $325.00

Human BDNF Protein (Recombinant GST) (Full Length) - LS-G27622
Wheat Germ Extract
GST
52.91 kDa
2µg  $385.00
12.5% SDS-PAGE of human BDNF stained with Coomassie Blue

Human BDNF Protein (Recombinant GST) (Full Length) - LS-G27623
Wheat Germ Extract
GST
55.3 kDa
2µg  $385.00
12.5% SDS-PAGE of human BDNF stained with Coomassie Blue
Showing 1-25 of 76 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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