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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BDNF

brain-derived neurotrophic factor

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Gene Name: brain-derived neurotrophic factor
Family/Subfamily: NGF Beta , not assigned-NGF Beta
Synonyms: BDNF, ANON2, Abrineurin, BULN2, Neurotrophin
Target Sequences: NM_001709 NP_001700.2 P23560

Publications (1)

1
Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats. McCarthy CA, Vinh A, Miller AA, Hallberg A, Alterman M, Callaway JK, Widdop RE. PloS one. 2014 9:e95762. (Flo; Rat) [Full Text Article] [PubMed:24752645] [PMC:PMC3994132] Related Antibodies: LS-B3815.

Filtered By: None
Target
BDNF (223)
Reactivity
Human (121)
Mouse (72)
Rat (93)
Bovine (6)
Chicken (9)
Chimpanzee (5)
Dog (22)
Gibbon (3)
Goat (24)
Guinea pig (15)
Hamster (10)
Horse (41)
Monkey (11)
Pig (62)
Rabbit (40)
Xenopus (5)
Zebrafish (4)
Application
IHC (78)
IHC-Fr (2)
IHC-P (5)
WB (210)
Flo (2)
ELISA (45)
ICC (12)
IF (8)
IP (12)
Neut (1)
Host
rabbit (166)
mouse (39)
goat (1)
chicken (3)
guinea pig (10)
sheep (4)
Isotype
IgG (139)
IgG1 (4)
IgG2a,k (1)
IgG2b (1)
IgG2b,k (24)
IgY (2)
Clonality
monoclonal mc (39)
polyclonal pc (184)
Clone
1B10 (1)
3D9C5 (1)
TS106 (1)
Format
AP Conjugated (3)
APC (15)
APC Conjugated (17)
Biotin Conjugated (32)
Cy3 Conjugated (15)
Cy7 Conjugated (15)
FITC Conjugated (31)
HRP Conjugated (23)
Magnetic beads Conjugated (1)
PE Conjugated (18)
Sepharose Conjugated (1)
Unconjugated (67)
Epitope
aa117-248 (10)
aa128-243 (10)
aa128-247 (10)
aa139-249 (10)
aa147-249 (10)
aa16-183 (10)
aa20-252 (10)
aa129-247 (9)
aa134-238 (9)
aa146-195 (4)
aa150-199 (4)
N-Terminus (2)
C-Terminus (1)
Internal (1)
aa129-138 (1)
aa129-148 (1)
aa131-150 (1)
aa162-176 (1)
aa183-194 (1)
aa19-247 (1)
aa19-248 (1)
aa20-70 (1)
aa206-236 (1)
aa69-82 (1)
Publications
No (222)
Yes (1)
Showing 1-25 of 223 results

BDNF Antibody (aa183-194) IHC-plus™ LS-B3815
Publications (1)
Publications (1)
Goat Polyclonal to Human BDNF
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC IHC-P
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-BDNF antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3815 concentration 3.75 ug/ml.
Anti-BDNF antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3815 concentration 3.75 ug/ml.

BDNF Antibody IHC-plus™ LS-B11849
Chicken Polyclonal (IgY) to Mouse BDNF
Mouse, Rat, Human
IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $425.00
Mouse Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Mouse Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
Mouse Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Mouse Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)

BDNF Antibody LS-C104728
Rabbit Polyclonal to Human BDNF
Mouse, Rat, Human
ELISA WB
Unconjugated
50µg  $285.00; 100µg  $325.00
Anti-Human/Murine/Rat BDNF Western Blot Reduced
Anti-Human/Murine/Rat BDNF Western Blot Unreduced
Anti-Human/Murine/Rat BDNF Western Blot Reduced
Anti-Human/Murine/Rat BDNF Western Blot Unreduced

BDNF Antibody LS-C35180
Mouse Monoclonal (IgG1) to Human BDNF
Human
ELISA Neut WB
Unconjugated
100µg 1mg/ml  $755.00

BDNF Antibody LS-C77177
Mouse Monoclonal (IgG1) to Human BDNF
Human
ELISA WB
Unconjugated
100µg 0.5mg/ml  $620.00

BDNF Antibody (aa206-236) LS-C99792
Rabbit Polyclonal to Human BDNF
Human
Flo IF IHC IHC-P WB
Unconjugated
400µl  $305.00
Formalin-fixed and paraffin-embedded human brain reacted with BDNF Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Confocal immunofluorescence of BDNF Antibody with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Formalin-fixed and paraffin-embedded human brain reacted with BDNF Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Confocal immunofluorescence of BDNF Antibody with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

BDNF Antibody LS-C4222
Mouse Monoclonal (IgG) to Human BDNF
Human
ELISA
Unconjugated
500µg  $445.00

BDNF Antibody LS-C77181
Rabbit Polyclonal to Human BDNF
Rat, Human
ELISA IHC WB
Unconjugated
100µl  $590.00

BDNF Antibody LS-C211630
Rabbit Polyclonal (IgG) to Human BDNF
Human
ELISA WB
Unconjugated
50µg  $285.00; 100µg 1mg/ml  $385.00

BDNF Antibody (Biotin) LS-C211634
Rabbit Polyclonal (IgG) to Human BDNF
Human
ELISA WB
Biotin Conjugated
50µg  $285.00; 100µg 0.25mg/ml  $385.00

BDNF Antibody (FITC) LS-C211633
Rabbit Polyclonal (IgG) to Human BDNF
Human
ELISA WB
FITC Conjugated
50µg  $285.00; 100µg 0.25mg/ml  $385.00

BDNF Antibody (aa19-248, clone 3D9C5) LS-C285902
Mouse Monoclonal [clone 3D9C5] (IgG1) to Human BDNF
Human
ELISA IF WB
Unconjugated
100µg 1mg/ml  $365.00
Immunofluorescence of HeLa cells using BDNF mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)
Western blot using BDNF monoclonal antibody against human BDNF (AA: 19-248) recombinant protein. (Expected MW is 51.7 kDa)
Immunofluorescence of HeLa cells using BDNF mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)
Western blot using BDNF monoclonal antibody against human BDNF (AA: 19-248) recombinant protein. (Expected MW is 51.7 kDa)

BDNF Antibody LS-C497469
Rabbit Monoclonal to Human BDNF
Mouse, Rat, Human
IF IHC WB
Unconjugated
50µl  $295.00; 100µl  $385.00; 200µl  $560.00
Immunohistochemistry of paraffin-embedded mouse brain using BDNF antibodyat dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human lung using BDNF antibodyat dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using BDNF antibodyat dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human lung using BDNF antibodyat dilution of 1:100 (40x lens).

BDNF Antibody (aa129-247) LS-C343943
Rabbit Polyclonal to Human BDNF
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $325.00
BDNF antibody IHC-paraffin: Rat Brain Tissue.
BDNF antibody IHC-paraffin: Mouse Brain Tissue.
BDNF antibody IHC-paraffin: Rat Brain Tissue.
BDNF antibody IHC-paraffin: Mouse Brain Tissue.

BDNF Antibody (aa19-247, clone TS106) LS-C191425
Mouse Monoclonal [clone TS106] (IgG2b) to Human BDNF
Mouse, Human
IHC WB
Unconjugated
100µg 200µl 0.5mg/ml  $620.00

BDNF Antibody LS-C93950
Rabbit Polyclonal to Human BDNF
Mouse, Rat, Human
IHC WB
Unconjugated
50µg 100µl 0.5mg/ml  $325.00

BDNF Antibody LS-C192703
Rabbit Polyclonal to Human BDNF
Mouse, Rat, Human
IHC WB
Unconjugated
100µl  $385.00
Western blot of extracts of SH-SY5Y cell and PC-12 cell lines, using BDNF antibody.
Western blot of extracts of SH-SY5Y cell and PC-12 cell lines, using BDNF antibody.

BDNF Antibody LS-C77182
Sheep Polyclonal to Human BDNF
Mouse, Rat, Human
ELISA IHC
Unconjugated
500µg  $590.00

BDNF Antibody LS-C77170
Rabbit Polyclonal (IgG1) to Human BDNF
Human
ELISA WB
Unconjugated
100µg  $740.00

BDNF Antibody (C-Terminus) LS-C347618
Rabbit Polyclonal (IgG) to Human BDNF
Human
Flo IF IHC WB
Unconjugated
100µl  $405.00

BDNF Antibody (clone 1B10) LS-C196746
Mouse Monoclonal [clone 1B10] (IgG2a,k) to Human BDNF
Human
ELISA IF IP WB
Unconjugated
100µg  $355.00
Immunofluorescence of monoclonal antibody to BDNF on HeLa cell . [antibody concentration 10 ug/ml]
BDNF monoclonal antibody (M02), clone 1B10. Western Blot analysis of BDNF expression in IMR-32.
Immunofluorescence of monoclonal antibody to BDNF on HeLa cell . [antibody concentration 10 ug/ml]
BDNF monoclonal antibody (M02), clone 1B10. Western Blot analysis of BDNF expression in IMR-32.

BDNF Antibody LS-C331411
Rabbit Polyclonal (IgG) to Human BDNF
Mouse, Rat, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded rat lung using BDNF antibody at dilution of 1:100 (200x lens).
Immunohistochemistry of paraffin-embedded human esophagus using BDNF antibody at dilution of 1:100 (200x lens).
Immunohistochemistry of paraffin-embedded rat lung using BDNF antibody at dilution of 1:100 (200x lens).
Immunohistochemistry of paraffin-embedded human esophagus using BDNF antibody at dilution of 1:100 (200x lens).

BDNF Antibody (aa20-70) LS-C483057
Rabbit Polyclonal to Mouse BDNF
Mouse, Rat
IHC WB
Unconjugated
100µl  $325.00
Rabbit antibody to pro BDNF (20-70). IHC-P on paraffin sections of rat DRG. The animal was perfused using Autoperfuser at a pressure of 130 mm Hg with 300 ml 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through a 0.2 micron filter. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions, using DAB chromogen. Primary antibody: dilution 1:1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin. Small neurons are stained and also some nuclear staining is observed.
Rabbit antibody to pro BDNF (20-70). IHC-P on paraffin sections of rat DRG. The animal was perfused using Autoperfuser at a pressure of 130 mm Hg with 300 ml 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through a 0.2 micron filter. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions, using DAB chromogen. Primary antibody: dilution 1:1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin. Small neurons are stained and also some nuclear staining is observed.
Rabbit antibody to pro BDNF (20-70). IHC-P on paraffin sections of rat DRG. The animal was perfused using Autoperfuser at a pressure of 130 mm Hg with 300 ml 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through a 0.2 micron filter. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions, using DAB chromogen. Primary antibody: dilution 1:1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin. Small neurons are stained and also some nuclear staining is observed.
Rabbit antibody to pro BDNF (20-70). IHC-P on paraffin sections of rat DRG. The animal was perfused using Autoperfuser at a pressure of 130 mm Hg with 300 ml 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through a 0.2 micron filter. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions, using DAB chromogen. Primary antibody: dilution 1:1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin. Small neurons are stained and also some nuclear staining is observed.

BDNF Antibody LS-C747183
Rabbit Polyclonal (IgG) to Human BDNF
Rat, Human
IF IHC WB
Unconjugated
50µl  $265.00

BDNF Antibody LS-C746869
Rabbit Polyclonal (IgG) to Human BDNF
Mouse, Rat, Human
IF IHC
Unconjugated
50µl  $235.00
Immunohistochemistry of paraffin-embedded rat brain using BDNF antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using BDNF antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using BDNF antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using BDNF antibody at dilution of 1:100 (40x lens).
Showing 1-25 of 223 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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