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BDKRB2/Bradykinin B2 Receptor

bradykinin receptor B2

BDKRB2/Bradykinin B2 Receptor is a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.

Gene Name: bradykinin receptor B2
Family/Subfamily: GPCR , Bradykinin
Synonyms: BDKRB2, BK-2 receptor, Bradykinin type-2 receptor, B2R, Bradykinin B2 receptor, BRB2, BK-2R, BK-2Rs, BK2, B2 bradykinin receptor, B2bkr, BK-2, BKR2, Bradykinin receptor B2
Target Sequences: NM_000623 NP_000614.1 P30411

Publications (4)

1
Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation. Savard M, Barbaz D, Blanger S, Mller-Esterl W, Bkaily G, D'orlans-Juste P, Cot J, Bovenzi V, Gobeil F. Journal of cellular physiology. 2008 216:234-44. (Mouse, Human, Rat) [Full Text Article] [PubMed:18264983] Related Antibodies: LS-A797.
2
Immunohistochemical localization of the bradykinin B1 and B2 receptors in human nasal mucosa. Shirasaki H, Kanaizumi E, Himi T. Mediators of inflammation. 2009 2009:102406. (IHC-P; Human) [Full Text Article] [PubMed:19404481] [PMC:PMC2673475] Related Antibodies: LS-A797.
3
Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer. Dubuc C, Savard M, Bovenzi V, Lessard A, Fortier A, Côté J, Neugebauer W, Rizzolio F, Geha S, Giordano A, Chemtob S, Gobeil F. Oncotarget. 2018 January;9:9885-9906. (Human) [Full Text Article] [PubMed:29515778] [PMC:PMC5839409] Related Antibodies: LS-A797.
4
Structure-activity relationships of novel peptide agonists of the human bradykinin B2 receptor. B[Character e9]langer S, Bovenzi V, C[Character f4]t[Character e9] J, Neugebauer W, Amblard M, Martinez J, Lammek B, Savard M, Gobeil F. Peptides. 2009 Apr;30:777-87. [Full Text Article] [PubMed:19111586] Related Antibodies: LS-A797.
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BDKRB2/Bradykinin B2 Receptor (2)
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BDKRB2/Bradykinin B2 Receptor Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Human BDKRB2/Bradykinin B2 Receptor Protein (Recombinant GST, N-terminus) (aa1-60) - LS-G57888
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
BDKRB2/Bradykinin B2 Receptor Protein - 12.5% SDS-PAGE of human BDKRB2 stained with Coomassie Blue
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Human BDKRB2/Bradykinin B2 Receptor Protein (Recombinant GST) (Full Length) - LS-G27621
Wheat Germ Extract
GST
70.9 kDa
2 µg/$439
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