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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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BCL2L11 / BIM

BCL2-like 11 (apoptosis facilitator)

BCL2L11 / BIM belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Gene Name: BCL2-like 11 (apoptosis facilitator)
Family/Subfamily: Apoptosis
Synonyms: BCL2L11, BIM-alpha6, BIM-beta7, Bcl-2-like protein 11, BIM-beta6, BimL, BimS, Bcl-2 interacting protein Bim, BimEL, BAM, Bcl2-L-11, BIM, BOD
Target Sequences: NM_006538 O43521 O43521


BCL2L11 / BIM Antibody - Anti-BCL2L11 / BIM antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human BCL2L11 / BIM
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $545.00
BCL2L11 / BIM Antibody - Anti-BCL2L11 / BIM antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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Rabbit Polyclonal to Human BCL2L11 / BIM
Human
Flo, IHC, IHC-P, WB
Unconjugated
200µl   $425.00
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Rabbit Polyclonal to Human BCL2L11 / BIM
Human, Monkey
ELISA, Flo, IF, IP, WB
Unconjugated
100µl   $530.00
BCL2L11 / BIM Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BIM Antibody. The picture on the right is blocked with the synthesized peptide.
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Rabbit Polyclonal (IgG) to Human BCL2L11 / BIM
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
BCL2L11 / BIM Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Mouse Monoclonal [clone 1C2C8] (IgG1) to Human BCL2L11 / BIM
Mouse, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $365.00
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Rabbit Monoclonal (IgG) to Human BCL2L11 / BIM
Human
ELISA, IP, WB
Biotin Conjugated, Preservative Free
50µg   $295.00
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Rabbit Monoclonal (IgG) to Human BCL2L11 / BIM
Human
ELISA, IP, WB
Unconjugated, Preservative Free
20µg   $195.00; 100µg   $265.00; 200µg   $295.00; 500µg   $415.00
BCL2L11 / BIM Antibody - Immunohistochemical analysis of BIM (pS69) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
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Rabbit Polyclonal to Human BCL2L11 / BIM
Mouse, Sheep, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $265.00
BCL2L11 / BIM Antibody - Immunohistochemistry of Bim in human skin cancer cells with Bim antibody at 20 µg/ml.
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Rabbit Polyclonal (IgG) to Human BCL2L11 / BIM
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1mg   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human BCL2L11 / BIM
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human BCL2L11 / BIM
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl   $740.00
BCL2L11 / BIM Antibody - Western blot analysis of Bim in K562 (Left) and A549 (Right) whole cell lysates using a 1:1000 dilution of BCL2L11 / BIM antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human BCL2L11 / BIM
Mouse, Rat, Human
IHC, WB
Biotin Conjugated
100µg   1mg/ml   $375.00
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Rat Monoclonal (IgG2a) to Mouse BCL2L11 / BIM
Mouse, Hamster, Pig, Human, Monkey
ELISA, Flo, ICC, IHC, IP, WB
Unconjugated
100µg   $680.00
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Rabbit Polyclonal (IgG) to Human BCL2L11 / BIM
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50µg   $295.00
BCL2L11 / BIM Antibody - Antibody staining (0.5 ug/ml) of K562lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
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Goat Polyclonal to Human BCL2L11 / BIM
Human
Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
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Mouse Monoclonal (IgG1,k) to Human BCL2L11 / BIM
Human
ELISA
Unconjugated
100µg   $560.00
Select
Mouse Monoclonal (IgG1,k) to Human BCL2L11 / BIM
Human
ELISA
Biotin Conjugated
100µl   $710.00
BCL2L11 / BIM Antibody - A) Western blot using anti-Bim, mAb (10B12) detecting EE mouse BimS, BimL, BimEL and EE human, BimSS, BimS, BimLS, BimL, BimELS, BimEL. Probing with an anti-Hsp-70 mAb was used as a loading control for all blots. B) Western blot using anti-Bim, mAb (10B12) detecting endogenous Bim expression in mouse tissues but not in Bim knockout mice. Bim protein was revealed in lysates from mouse tissues (5 x 106/lane) and detection by ECL. Probing with an anti-Hsp-70 mAb was used as a loading control.
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Rat Monoclonal [clone 10B12] (IgG2a,k) to Mouse BCL2L11 / BIM
Mouse, Dog, Rat, Human, Monkey
ELISA, Flo, ICC, IHC, IP, WB
Unconjugated
100µg   $385.00
BCL2L11 / BIM Antibody - A) Western blot using anti-Bim, mAb (3C5) detecting EE mouse BimS, BimL, BimEL and EE human, BimSS, BimS, BimLS, BimL, BimELS, BimEL. Probing with an anti-Hsp-70 mAb was used as a loading control for all blots. B) Western blot using anti-Bim, mAb (3C5) detecting endogenous Bim expression in mouse tissues but not in Bim knockout mice. Bim protein was revealed in lysates from mouse tissues (5 x 106/lane) and detection by ECL. Probing with an anti-Hsp-70 mAb was used as a loading control.
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Rat Monoclonal [clone 3C5] (IgG2a,k) to Mouse BCL2L11 / BIM
Mouse, Dog, Rat, Human, Monkey
ELISA, Flo, ICC, IHC, IP, WB
Unconjugated
100µg   $385.00
BCL2L11 / BIM Antibody - Immunohistochemistry analysis of human testis tissue at a dilution of 1:100
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Rabbit Polyclonal (IgG) to Human BCL2L11 / BIM
Human
ELISA, ICC, IF, IHC
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rat Monoclonal (IgG2b) to Mouse BCL2L11 / BIM
Mouse, Human, Monkey
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
100µg   $620.00
Select
Rat Monoclonal (IgG2a) to Mouse BCL2L11 / BIM
Mouse, Human, Monkey
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
100µg   $680.00
BCL2L11 / BIM Antibody - Immunocytochemistry of BIM EL inK562 cells with BIM EL antibody at 2.5 ug/ml.
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Rabbit Polyclonal (IgG) to Human BCL2L11 / BIM
Mouse, Rat, Human
ELISA, ICC, IF, WB
Unconjugated
0.1mg   1mg/ml   $375.00
Select
Mouse Monoclonal [clone 1C2H4] (IgG1) to Human BCL2L11 / BIM
Mouse, Rat, Human
ELISA, ICC, IF, WB
Unconjugated
0.1mg   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human BCL2L11 / BIM
Mouse, Rat, Human
WB
HRP Conjugated
100µl   $770.00
Viewing 1-25 of 130 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).