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BCL2L10 / Diva

BCL2-like 10 (apoptosis facilitator)

BCL2L10 / Diva belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Gene Name: BCL2-like 10 (apoptosis facilitator)
Family/Subfamily: Apoptosis
Synonyms: BCL2L10, BCL-B, Apoptosis regulator Bcl-B, BCLB, Bcl2-L-10, Diva not vaccine, Anti-apoptotic protein NrH, Bcl-2-like protein 10, Boo, Boo not bladder, Diva
Target Sequences: NM_020396 NP_065129.1 Q9HD36

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Proteins (3)
Recombinant (3)
BCL2L10 / Diva (3)
No (3)
GST (1)
GST, N-terminus (1)
His (1)
Human (3)
E. coli (1)
Wheat Germ Extract (2)
Purified (2)
BCL2L10 / Diva Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
BCL2L10 / Diva Protein - 12.5% SDS-PAGE of human BCL2L10 stained with Coomassie Blue
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Wheat Germ Extract
GST
49.6 kDa
10 µg/$479; 25 µg/$670
BCL2L10 / Diva Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).