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BCL2L1 / BCL-XL

BCL2-like 1

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F1F0 activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles.Isoform Bcl-X(S) promotes apoptosis.

Gene Name: BCL2-like 1
Family/Subfamily: Apoptosis
Synonyms: BCL2L1, Apoptosis regulator Bcl-X, Bcl-xL, BCL-XL/S, BCLXS, Bcl-2-like protein 1, BCL2-like 1, BCL2L, Bcl-X, Bcl-xS, BCLXL, PPP1R52, Bcl2-L-1, BCLX
Target Sequences: NM_001191 NP_001182.1 Q07817

☰ Filters
Products
Proteins (18)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (5)
Recombinant (12)
BCL2L1 / BCL-XL (18)
No (18)
6His, C-terminus (1)
6His, N-terminus (2)
8His, N-terminus (1)
GST (1)
His (2)
His, N-Terminal (1)
His,C-terminus (2)
His-SUMO (1)
His-T7 (2)
Myc-DDK (Flag) (5)
Human (13)
Mouse (2)
Rat (1)
293T Cells (2)
E. coli (9)
HEK 293 Cells (6)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (2)
BCL2L1 / BCL-XL Protein - 12.5% SDS-PAGE of human BCL2L1 stained with Coomassie Blue
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Wheat Germ Extract
GST
51.37 kDa
10 µg/$479; 25 µg/$670
Select
293T Cells
Myc-DDK (Flag)
25.9 kDa
20 µg/$150
BCL2L1 / BCL-XL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
18.7 kDa
20 µg/$150
BCL2L1 / BCL-XL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
18.7 kDa
100 µg/$494
BCL2L1 / BCL-XL Protein
Select
E. coli
His-SUMO
39.4 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
HEK 293 Cells
6His, N-terminus
24.7 kDa
200 µl/$283
Select
HEK 293 Cells
8His, N-terminus
24.7 kDa
100 µg/$298
BCL2L1 / BCL-XL Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
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E. coli
6His, N-terminus
27 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 250 µg/$518
BCL2L1 / BCL-XL Protein - Purified recombinant protein BCL2L1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
25.9 kDa
20 µg/$1,107
Select
E. coli
His
25.2 kDa
100 µg/$793
BCL2L1 / BCL-XL Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.9 kDa
100 µg/$494
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E. coli
His,C-terminus
25.2 kDa
100 µg/$843
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E. coli
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.85 kDa
10 µg/$376; 50 µg/$526
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.85kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
BCL2L1 / BCL-XL Protein
Select
HEK 293 Cells
His, N-Terminal
25 kDa (~30 kDa reducing conditions)
10 µg/$289; 200 µg/$646; 50 µg/$360
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E. coli
His-T7
27.6 kDa
10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646
BCL2L1 / BCL-XL Protein - Recombinant B-Cell CLL/Lymphoma 2 Like Protein By SDS-PAGE
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E. coli
His-T7
27.5 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Select
E. coli
His
25.3 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
Viewing 1-18 of 18 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).