BCCIP

BRCA2 and CDKN1A interacting protein

BCCIP was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

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Products

Antibodies (12)

Type

Primary (12)

Target

BCCIP (12)

Reactivity

Human (12)

Mouse (2)

Rat (2)

Application

IHC (6)

IHC-P (1)

WB (10)

ELISA (2)

ICC (1)

IF (3)

IP (2)

Peptide-ELISA (1)

Host

rabbit (10)

mouse (2)

Isotype

IgG (9)

IgG2b (1)

Clonality

monoclonal mc (1)

polyclonal pc (11)

Format

Unconjugated (12)

Epitope

60-140 aa, Internal (1)

C-Terminus (1)

aa1-50 (1)

aa181-273 (1)

aa250-C-term (1)

aa300-350 (1)

Publications

No (12)

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BCCIP Antibody (aa181-273) LS-C186295

Antibody:

BCCIP Rabbit anti-Human Polyclonal (aa181-273) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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BCCIP Antibody (aa300-350) LS-C286842

Antibody:

BCCIP Rabbit anti-Human Polyclonal (aa300-350) Antibody

Reactivity:

Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

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BCCIP Antibody LS-C660094

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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BCCIP Antibody LS-C410121

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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BCCIP Antibody LS-C807819

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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BCCIP Antibody LS-C764817

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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BCCIP Antibody (aa250-C-term) LS-C288949

Antibody:

BCCIP Rabbit anti-Human Polyclonal (aa250-C-term) Antibody

Reactivity:

Human

Applications:

IHC, IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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BCCIP Antibody (60-140 aa, Internal) LS-C386456

Antibody:

BCCIP Rabbit anti-Human Polyclonal (60-140 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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BCCIP Antibody LS-C306519

Antibody:

BCCIP Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

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BCCIP Antibody (aa1-50) LS-C288948

Antibody:

BCCIP Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

BCCIP Antibody (C-Terminus) LS-C125207

Antibody:

BCCIP Mouse anti-Human Monoclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

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BCCIP Antibody LS-C668769

Antibody:

BCCIP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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