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BCAR3

Breast Cancer Anti-estrogen Resistance 3

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Breast Cancer Anti-estrogen Resistance 3
Synonyms: BCAR3, NSP2, SH2D3B, Novel SH2-containing protein 2
Target Sequences: NM_003567 NP_003558.1 O75815

☰ Filters
Antibodies (19)
ELISA Kits (6)
Proteins (5)
Cell-Based (1)
Custom (2)
Over-Expression Lysate (2)
Primary (19)
Recombinant (3)
Sandwich (3)
BCAR3 (30)
Human (21)
Mouse (7)
Rat (4)
Bovine (1)
Dog (2)
Monkey (1)
IHC (6)
IHC-P (3)
WB (19)
ELISA (3)
ICC (1)
IF (4)
IP (1)
Peptide-ELISA (2)
rabbit (17)
mouse (1)
goat (1)
IgG (5)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (18)
3G4 (1)
96-Well Microplate (1)
96-Well Strip Plate (5)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (12)
aa548-818 (8)
730-810 aa, C-terminal (1)
C-Terminus (1)
aa25-75 (1)
aa785-818 (1)
aa791-825 (1)
aa813-825 (1)
No (30)
Adherent Cell Cultures (1)
Plasma (3)
Serum (3)
Tissue Homogenates (2)
GST, N-terminus (1)
His-GST (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
BCAR3 Antibody - Immunohistochemical analysis of BCAR3 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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BCAR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Bovine, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$321
BCAR3 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BCAR3 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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BCAR3 Rabbit anti-Human Polyclonal (730-810 aa, C-terminal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
BCAR3 Antibody
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BCAR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
BCAR3 Antibody - BCAR3 was detected in paraffin-embedded sections of mouse lymphadenoma tissues using rabbit anti- BCAR3 Antigen Affinity purified polyclonal antibody at 1 ug/mL. The immunohistochemical section was developed using SABC method.
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BCAR3 Rabbit anti-Human Polyclonal (aa791-825) Antibody
Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
BCAR3 Antibody - Immunofluorescence of BCAR3 in human kidney tissue with BCAR3 antibody at 20 ug/ml.
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BCAR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
0.1 mg/$460
BCAR3 Antibody - Western blot of HeLa cell lysate using BCAR3 Antibody
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BCAR3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
BCAR3 Antibody - Detection limit for recombinant GST tagged BCAR3 is approximately 0.03 ng/ml as a capture antibody.
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BCAR3 Mouse anti-Human Monoclonal (3G4) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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BCAR3 Rabbit anti-Human Polyclonal (aa25-75) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
BCAR3 Antibody - BCAR3 antibody (0.5 ug/ml) staining of Mouse Kidney epithelial cells lysate (15 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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BCAR3 Goat anti-Human Polyclonal (aa813-825) Antibody
Mouse, Dog, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
BCAR3 Antibody - Western blot of lysates from mouse spleen tissue lysate with MOUSE Bcar3 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody.
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BCAR3 Rabbit anti-Mouse Polyclonal (aa785-818) Antibody
Mouse
WB
Unconjugated
400 µl/$393
BCAR3 Antibody - Western blot of BCAR3 antibody.
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BCAR3 Rabbit anti-Human Polyclonal (aa548-818) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
BCAR3 Antibody - Western blot of BCAR3 antibody.
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BCAR3 Rabbit anti-Human Polyclonal (aa548-818) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
BCAR3 Antibody - Western blot of BCAR3 antibody.
Select
BCAR3 Rabbit anti-Human Polyclonal (aa548-818) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
BCAR3 Antibody - Western blot of BCAR3 antibody.
Select
BCAR3 Rabbit anti-Human Polyclonal (aa548-818) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
BCAR3 Antibody - Western blot of BCAR3 antibody.
Select
BCAR3 Rabbit anti-Human Polyclonal (aa548-818) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
BCAR3 Antibody - Western blot of BCAR3 antibody.
Select
BCAR3 Rabbit anti-Human Polyclonal (aa548-818) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
BCAR3 Antibody - Western blot of BCAR3 antibody.
Select
BCAR3 Rabbit anti-Human Polyclonal (aa548-818) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
BCAR3 Antibody - Western blot of BCAR3 antibody.
Select
BCAR3 Rabbit anti-Human Polyclonal (aa548-818) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
BCAR3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
BCAR3 Protein - Purified recombinant protein BCAR3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
92.4 kDa
20 µg/$1,107
BCAR3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.4 kDa
20 µg/$150
BCAR3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
BCAR3 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
BCAR3 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
Viewing 1-25 of 30 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).