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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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BBS5

Bardet-Biedl syndrome 5

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.

Gene Name: Bardet-Biedl syndrome 5
Synonyms: BBS5, Bardet-Biedl syndrome 5
Target Sequences: Q8N3I7 Q8N3I7

Viewing 1-15 of 15 items
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Rabbit Polyclonal (IgG) to Human BBS5
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg   $405.00
BBS5 Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Rabbit Polyclonal (IgG) to Human BBS5
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Mouse Monoclonal (IgG2a) to Human BBS5
Human
ELISA, WB
Unconjugated
100µg   $405.00
Select
Rabbit Polyclonal (IgG) to Human BBS5
Human
WB
Unconjugated
100µl   $295.00; 200µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human BBS5
Human
WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00
BBS5 Antibody - Western blot of lysate from K562 cell line with BBS5 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.
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Rabbit Polyclonal to Human BBS5
Human
WB
Unconjugated
400µl   $325.00
BBS5 Antibody - BBS5 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human BBS5
Xenopus, Chicken, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
BBS5 Antibody - BBS5 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human BBS5
Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
BBS5 Antibody - BBS5 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human BBS5
Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100µl   1mg/ml   $385.00
BBS5 Antibody - BBS5 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human BBS5
Xenopus, Chicken, Zebrafish, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Rat, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100µl   1mg/ml   $385.00
BBS5 Antibody - BBS5 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human BBS5
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
BBS5 Antibody - BBS5 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human BBS5
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
BBS5 Antibody - BBS5 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human BBS5
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100µl   1mg/ml   $385.00
BBS5 Antibody - BBS5 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human BBS5
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100µl   1mg/ml   $385.00
Select
Mouse Polyclonal (IgG) to Human BBS5
Human
WB
Unconjugated
50µg   $560.00

Viewing 1-15 of 15 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).