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BBS2 / BBS

Bardet-Biedl syndrome 2

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.

Gene Name: Bardet-Biedl syndrome 2
Synonyms: BBS2, Bardet-Biedl syndrome 2, BBS
Target Sequences: NM_031885 NP_114091.3 Q9BXC9

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Products
Antibodies (17)
Primary (17)
BBS2 / BBS (17)
Human (15)
Mouse (6)
Rat (3)
Bat (6)
Bovine (6)
Chicken (3)
Chimpanzee (3)
Dog (6)
Gibbon (6)
Guinea pig (3)
Horse (6)
Monkey (3)
Orangutan (6)
Rabbit (6)
Zebrafish (6)
IHC (4)
IHC-P (2)
WB (16)
ELISA (4)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (15)
mouse (2)
IgG (7)
IgG2a (1)
monoclonal mc (1)
polyclonal pc (16)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (11)
aa151-200 (4)
aa315-364 (4)
No (17)
BBS2 / BBS Antibody - Immunohistochemistry of paraffin-embedded human endometrial cancer at dilution 1:100
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BBS2 / BBS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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BBS2 / BBS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$331
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BBS2 / BBS Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$351
BBS2 / BBS Antibody - Immunohistochemistry of paraffin-embedded human endometrial cancer at dilution 1:100
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BBS2 / BBS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
BBS2 / BBS Antibody - 1:100 staining mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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BBS2 / BBS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
BBS2 / BBS Antibody - Western blot analysis of extracts of various cell lines.
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BBS2 / BBS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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BBS2 / BBS Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
BBS2 / BBS Antibody - BBS2 antibody Western blot of COLO205 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BBS2 / BBS Rabbit anti-Human Polyclonal (aa315-364) Antibody
Human
WB
Unconjugated
100 µl/$424
BBS2 / BBS Antibody - BBS2 antibody Western blot of COLO205 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BBS2 / BBS Rabbit anti-Human Polyclonal (aa315-364) (HRP) Antibody
Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Human, Gibbon, Orangutan
WB
HRP Conjugated
100 µl/$469
BBS2 / BBS Antibody - BBS2 antibody Western blot of COLO205 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BBS2 / BBS Rabbit anti-Human Polyclonal (aa315-364) (Biotin) Antibody
Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Human, Gibbon, Orangutan
WB
Biotin Conjugated
100 µl/$469
BBS2 / BBS Antibody - BBS2 antibody Western blot of COLO205 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BBS2 / BBS Rabbit anti-Human Polyclonal (aa315-364) (FITC) Antibody
Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Human, Gibbon, Orangutan
WB
FITC Conjugated
100 µl/$469
BBS2 / BBS Antibody - BBS2 antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BBS2 / BBS Rabbit anti-Human Polyclonal (aa151-200) Antibody
Human
WB
Unconjugated
100 µl/$424
BBS2 / BBS Antibody - BBS2 antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BBS2 / BBS Rabbit anti-Human Polyclonal (aa151-200) (HRP) Antibody
Zebrafish, Horse, Rabbit, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
HRP Conjugated
100 µl/$469
BBS2 / BBS Antibody - BBS2 antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BBS2 / BBS Rabbit anti-Human Polyclonal (aa151-200) (Biotin) Antibody
Zebrafish, Horse, Rabbit, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
BBS2 / BBS Antibody - BBS2 antibody Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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BBS2 / BBS Rabbit anti-Human Polyclonal (aa151-200) (FITC) Antibody
Zebrafish, Horse, Rabbit, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
FITC Conjugated
100 µl/$469
BBS2 / BBS Antibody - Western blot analysis of BBS2 expression in mouse testis (A); mouse kidney (B); rat liver (C); rat brain (D) whole cell lysates.
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BBS2 / BBS Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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BBS2 / BBS Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-17 of 17 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).