BAZ2A / TIP5

bromodomain adjacent to zinc finger domain, 2A

Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing.

☰ Filters

Products

Antibodies (8)

Type

Primary (8)

Target

BAZ2A / TIP5 (8)

Reactivity

Human (8)

Application

WB (4)

ELISA (6)

IF (2)

Peptide-ELISA (2)

Host

rabbit (8)

Isotype

IgG (8)

Clonality

polyclonal pc (8)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (5)

Epitope

1250-1330 aa, Internal (1)

aa1244-1293 (1)

Publications

No (8)

Select

BAZ2A / TIP5 Antibody (aa1244-1293) LS-C200177

Antibody:

BAZ2A / TIP5 Rabbit anti-Human Polyclonal (aa1244-1293) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

BAZ2A / TIP5 Antibody LS-C677280

Antibody:

BAZ2A / TIP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

BAZ2A / TIP5 Antibody (HRP) LS-C677277

Antibody:

BAZ2A / TIP5 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

BAZ2A / TIP5 Antibody (Biotin) LS-C677279

Antibody:

BAZ2A / TIP5 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

BAZ2A / TIP5 Antibody (FITC) LS-C677278

Antibody:

BAZ2A / TIP5 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

BAZ2A / TIP5 Antibody LS-C804875

Antibody:

BAZ2A / TIP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

BAZ2A / TIP5 Antibody LS-C742644

Antibody:

BAZ2A / TIP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

BAZ2A / TIP5 Antibody (1250-1330 aa, Internal) LS-C386422

Antibody:

BAZ2A / TIP5 Rabbit anti-Human Polyclonal (1250-1330 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Viewing 1-8 of 8 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Antibodies

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.