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BATF2 / SARI

basic leucine zipper transcription factor, ATF-like 2

AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8+ thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes By similarity. Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.

Gene Name: basic leucine zipper transcription factor, ATF-like 2
Synonyms: BATF2, B-ATF-2, SARI
Target Sequences: Q8N1L9 Q8N1L9

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
BATF2 / SARI (4)
No (4)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
BATF2 / SARI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
29.2 kDa
100 µg/$494
BATF2 / SARI Protein
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E. coli
His, N-Terminal
29.2 kDa
50 µg/$419
BATF2 / SARI Protein - 12.5% SDS-PAGE of human MGC20410 stained with Coomassie Blue
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Wheat Germ Extract
GST
46.53 kDa
10 µg/$479; 25 µg/$670
BATF2 / SARI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
29.2 kDa
20 µg/$150
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).