BAG4 / SODD

BCL2-associated athanogene 4

BAG4 / SODD is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

BAG4 / SODD (7)

Publications

No (7)

Tag

GST (2)

GST, N-terminus (1)

His-T7, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Purification

Purified (2)

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Human BAG4 / SODD Protein (Recombinant GST, N-terminus) (aa231-340) - LS-G61162

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human BAG4 / SODD Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68473

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.4 kDa

Price:

20 µg/$1,107

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Human BAG4 / SODD Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82264

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.4 kDa

Price:

20 µg/$150

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Human BAG4 / SODD Protein (Recombinant GST) (Full Length) - LS-G31681

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76.01 kDa

Price:

10 µg/$479; 25 µg/$670

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Human BAG4 / SODD Protein (Recombinant GST) (Full Length) - LS-G31684

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76 kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse BAG4 / SODD Protein (Recombinant His-T7, N-terminus) (Ser210-Ala447) - LS-G133451

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

29.5kDa

Price:

10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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BAG4 / SODD Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116354

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.4 kDa

Price:

100 µg/$494

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