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BACE2

beta-site APP-cleaving enzyme 2

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.

Gene Name: beta-site APP-cleaving enzyme 2
Family/Subfamily: Protease , Aspartic A1
Synonyms: BACE2, 56 kDa aspartic-like protease, AEPLC, ALP56, Aspartic-like protease 56 kDa, APL56, BAE2, Beta-secretase 2, ASP21, CDA13, DRAP, Memapsin-1, Asp 1, ASP1, Aspartyl protease 1, Theta-secretase, Beta secretase 2, CEAP1, Down region aspartic protease
Target Sequences: NM_012105 NP_036237.2 Q9Y5Z0

☰ Filters
Products
Proteins (12)
Over-Expression Lysate (6)
Recombinant (6)
BACE2 (12)
No (12)
GST, N-terminus (1)
His (2)
His-GST (2)
Myc-DDK (Flag) (7)
Human (6)
Mouse (2)
Rat (1)
293T Cells (3)
E. coli (3)
HEK 293 Cells (4)
Human Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
BACE2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
56.18 kDa
20 µg/$150
BACE2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
43.9 kDa
20 µg/$215
BACE2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.6 kDa
20 µg/$150
BACE2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
43.9 kDa
100 µg/$710
BACE2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
36.6 kDa
100 µg/$494
BACE2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
56.18 kDa
100 µg/$494
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E. coli
His
19.9 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
BACE2 Protein - Purified recombinant protein BACE2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
49.8 kDa
20 µg/$1,107
BACE2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
49.2 kDa
100 µg/$1,259; 1 mg/$6,240
BACE2 Protein - Recombinant Beta-Site APP Cleaving Enzyme 2 By SDS-PAGE
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E. coli
His-GST
59.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
BACE2 Protein - Recombinant Beta-Site APP Cleaving Enzyme 2 By SDS-PAGE
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E. coli
His-GST
60.9 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Viewing 1-12 of 12 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).