BABAM1 / HSPC142

BRISC and BRCA1 A complex member 1

Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36 component.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

BABAM1 / HSPC142 (8)

Publications

No (8)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (6)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human BABAM1 / HSPC142 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85991

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.4 kDa

Price:

20 µg/$150

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Human BABAM1 / HSPC142 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85992

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.4 kDa

Price:

20 µg/$150

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Human BABAM1 / HSPC142 Protein (Recombinant GST) (Full Length) - LS-G33395

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63 kDa

Price:

10 µg/$479; 25 µg/$670

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BABAM1 / HSPC142 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114128

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.4 kDa

Price:

100 µg/$494

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Human BABAM1 / HSPC142 Protein (Recombinant His) - LS-G2994

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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Human BABAM1 / HSPC142 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69979

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.4 kDa

Price:

20 µg/$1,107

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Human BABAM1 / HSPC142 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69980

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.4 kDa

Price:

20 µg/$1,107

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BABAM1 / HSPC142 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120928

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.4 kDa

Price:

100 µg/$494

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