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B4GALT6

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6

B4GALT6 is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis.

Gene Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
Synonyms: B4GALT6, Beta4GalT-VI, B4Gal-T6, Beta-1,4-GalTase 6, Beta4Gal-T6
Target Sequences: NM_004775 NP_004766.2 Q9UBX8

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Proteins (2)
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B4GALT6 (2)
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GST (1)
GST, N-terminus (1)
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Wheat Germ Extract (2)
Purified (1)
B4GALT6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
B4GALT6 Protein - 12.5% SDS-PAGE of human B4GALT6 stained with Coomassie Blue
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Wheat Germ Extract
GST
66.5 kDa
2 µg/$439
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).