B4GALT1

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1

B4GALT1 is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.

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Products

Antibodies (19)

ELISA Kits (8)

Proteins (8)

Type

Custom (5)

Over-Expression Lysate (2)

Primary (19)

Recombinant (6)

Sandwich (3)

Target

B4GALT1 (35)

Reactivity

Human (23)

Mouse (7)

Rat (3)

Bovine (1)

Monkey (1)

Application

IHC (3)

IHC-P (3)

WB (13)

Flo (1)

ELISA (14)

ICC (1)

IF (2)

IP (1)

Peptide-ELISA (1)

Host

rabbit (16)

mouse (3)

Product Group

IHCPlus (1)

Isotype

IgG (11)

IgG2b (1)

Clonality

monoclonal mc (3)

polyclonal pc (16)

Format

96-Well Microplate (1)

96-Well Strip Plate (6)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (14)

Epitope

aa329-358 (7)

C-Terminus (1)

C-terminal (1)

aa44-398 (1)

Publications

No (35)

Sample Type

Cell Culture Supernatants (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (2)

Serum (3)

Tissue Homogenates (2)

Tag

6His, C-terminus (1)

GST (1)

GST, N-terminus (2)

GST, N-terminus + His, C-terminus (1)

His,N-terminus (1)

Myc-DDK (Flag) (2)

Species

Bovine (2)

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Human (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (2)

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B4GALT1 Antibody (C-Terminus) LS-C368884

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Bovine, Rat, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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B4GALT1 Antibody (aa44-398) LS-C36410

Antibody:

B4GALT1 Mouse anti-Human Monoclonal (aa44-398) Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$896

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IHC-plus™ B4GALT1 Antibody LS-B16036

(4.0) Rating

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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B4GALT1 Antibody LS-C804857

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Human B4GALT1 (Sandwich ELISA) ELISA Kit - LS-F5021

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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B4GALT1 Antibody (aa329-358) LS-C156716

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal (aa329-358) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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B4GALT1 Antibody (C-terminal) LS-C386777

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal (C-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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B4GALT1 Antibody LS-C815957

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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B4GALT1 Antibody (aa329-358) LS-C330446

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal (aa329-358) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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B4GALT1 Antibody (aa329-358, Biotin) LS-C277504

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal (aa329-358) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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B4GALT1 Antibody (aa329-358, FITC) LS-C277502

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal (aa329-358) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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B4GALT1 Antibody (aa329-358, Azide-free, HRP) LS-C277505

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal (aa329-358) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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B4GALT1 Antibody (aa329-358, APC) LS-C277503

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal (aa329-358) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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B4GALT1 Antibody (aa329-358, PE) LS-C277507

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal (aa329-358) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

B4GALT1 Antibody LS-C823881

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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B4GALT1 Antibody LS-C483664

Antibody:

B4GALT1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

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B4GALT1 Antibody LS-C483665

Antibody:

B4GALT1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

B4GALT1 Antibody LS-C483662

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

B4GALT1 Antibody LS-C483660

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

B4GALT1 Antibody LS-C483663

Antibody:

B4GALT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

20 µl/$271; 100 µl/$412

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Human B4GALT1 (Custom ELISA) ELISA Kit - LS-F50429

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$672

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Human B4GALT1 Protein (Recombinant GST, N-terminus) (aa44-153) - LS-G58685

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human B4GALT1 (Sandwich ELISA) ELISA Kit - LS-F57335

Type:

Sandwich

Reactivity:

Human

Range:

156 - 10000 pg/ml

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$1,150

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Human B4GALT1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74750

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.7 kDa

Price:

20 µg/$150

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Mouse B4GALT1 (Custom ELISA) ELISA Kit - LS-F20429

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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