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B3GNT5

Udp-glcnac:betagal Beta-1,3-n-acetylglucosaminyltransferase 5

Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc4Cer; paragloboside), resulting in the synthesis of Lc3Cer and neolactopentaosylceramide (nLc5Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.

Gene Name: Udp-glcnac:betagal Beta-1,3-n-acetylglucosaminyltransferase 5
Synonyms: B3GNT5, Beta-1,3-Gn-T5, Lc(3)Cer synthase, Lc3 synthase, B3GN-T5, Beta3Gn-T5, BGnT-5, Lactotriaosylceramide synthase
Target Sequences: NM_032047 NP_114436.1 Q9BYG0

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).