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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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AZIN1

antizyme inhibitor 1

AZIN1 belongs to the antizyme inhibitor family, which plays a role in cell growth and proliferation by maintaining polyamine homeostasis within the cell. Antizyme inhibitors are homologs of ornithine decarboxylase (ODC, the key enzyme in polyamine biosynthesis) that have lost the ability to decarboxylase ornithine; however, retain the ability to bind to antizymes. Antizymes negatively regulate intracellular polyamine levels by binding to ODC and targeting it for degradation, as well as by inhibiting polyamine uptake. Antizyme inhibitors function as positive regulators of polyamine levels by sequestering antizymes and neutralizing their effect. This gene encodes antizyme inhibitor 1, the first member of this gene family that is ubiquitously expressed, and is localized in the nucleus and cytoplasm. Overexpression of antizyme inhibitor 1 gene has been associated with increased proliferation, cellular transformation and tumorigenesis. Gene knockout studies showed that homozygous mutant mice lacking functional antizyme inhibitor 1 gene died at birth with abnormal liver morphology. RNA editing of this gene, predominantly in the liver tissue, has been linked to the progression of hepatocellular carcinoma. Alternatively spliced transcript variants have been described for this gene.

Gene Name: antizyme inhibitor 1
Synonyms: AZIN1, Antizyme inhibitor, ODC1L, OAZI, Antizyme inhibitor 1, AZI, OAZIN
Target Sequences: NM_015878 NP_056962.2 O14977

Viewing 1-25 of 45 items
AZIN1 Antibody - Immunohistochemistry of paraffin-embedded human adrenal gland tissue using antibody at dilution of 1:100.
Select
Rabbit Polyclonal (IgG) to Human AZIN1
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human AZIN1
Mouse, Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human AZIN1
Mouse, Human
ELISA
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human AZIN1
Mouse, Human
ELISA
FITC Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG1) to Human AZIN1
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $405.00
AZIN1 Antibody - Immunochemical staining of human AZIN1 in human adrenal gland with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.
Select
Rabbit Polyclonal (IgG) to Human AZIN1
Human
ICC, IF, IHC-P
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
AZIN1 Antibody
Select
Rabbit Polyclonal (IgG) to Human AZIN1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
AZIN1 Antibody - Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-AZIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
Select
Mouse Monoclonal [clone OTI3C3] (IgG2b) to Human AZIN1
Human
IHC, WB
Unconjugated
100µl   1mg/ml   $345.00
AZIN1 Antibody - Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-AZIN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
Select
Mouse Monoclonal [clone OTI3C3] (IgG2b) to Human AZIN1
Human
IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Mouse Monoclonal (IgG2a,k) to Human AZIN1
Human
ELISA, WB
Unconjugated
100µg   $560.00
Select
Mouse Monoclonal (IgG2a,k) to Human AZIN1
Human
ELISA, WB
HRP Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human AZIN1
Human
ELISA, WB
Biotin Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human AZIN1
Human
ELISA, WB
FITC Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human AZIN1
Human
ELISA, WB
PE Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human AZIN1
Human
ELISA, WB
AP Conjugated
100µl   $710.00
Select
Mouse Monoclonal (IgG2a,k) to Human AZIN1
Human
ELISA, WB
APC Conjugated
100µl   $710.00
AZIN1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY AZIN1. (Right lane) cDNA for 48 hrs and lysed
Select
Mouse Monoclonal [clone OTI1D12] (IgG1) to Human AZIN1
Human
WB
Unconjugated
100µl   1mg/ml   $345.00
AZIN1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY AZIN1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AZIN1.
Select
Mouse Monoclonal [clone OTI1D12] (IgG1) to Human AZIN1
Human
WB
Unconjugated, Carrier-free
100µg   $395.00
AZIN1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY AZIN1. (Right lane) cDNA for 48 hrs and lysed
Select
Mouse Monoclonal [clone OTI1G8] (IgG1) to Human AZIN1
Human
WB
Unconjugated
100µl   1mg/ml   $345.00
AZIN1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY AZIN1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AZIN1.
Select
Mouse Monoclonal [clone OTI1G8] (IgG1) to Human AZIN1
Human
WB
Unconjugated, Carrier-free
100µg   $395.00
AZIN1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY AZIN1. (Right lane) cDNA for 48 hrs and lysed
Select
Mouse Monoclonal [clone OTI5C7] (IgG1) to Human AZIN1
Rat, Human
WB
Unconjugated
100µl   1mg/ml   $345.00
AZIN1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY AZIN1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AZIN1.
Select
Mouse Monoclonal [clone OTI5C7] (IgG1) to Human AZIN1
Rat, Human
WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Rabbit Polyclonal (IgG) to Human AZIN1
Human
WB
Unconjugated
100µg   $605.00
Select
Rabbit Polyclonal (IgG) to Human AZIN1
Human
WB
APC Conjugated
100µl   $755.00
AZIN1 Antibody - Western blot of AZIN1 antibody.
Select
Rabbit Polyclonal to Human AZIN1
Pig, Human
WB
Unconjugated
20µl   0.5mg/ml   $205.00; 100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $305.00; 1ml   0.5mg/ml   $530.00

Viewing 1-25 of 45 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).