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Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
Gene Name: | mitochondrially encoded ATP synthase 6 |
Synonyms: | MT-ATP6, ATP synthase 6, ATP synthase F0 subunit 6, ATPase-6, F-ATPase protein 6, MTATP6, Su6m, RP, ATP6, ATPase6 |
Target Sequences: | P00846 P00846 |
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