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ATP6V0A1

ATPase, H+ transporting, lysosomal V0 subunit a1

ATP6V0A1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: ATPase, H+ transporting, lysosomal V0 subunit a1
Family/Subfamily: Transporter , ATPase - V type
Synonyms: ATP6V0A1, ATP6N1, STV1, V-ATPase 116 kDa, VPP1, ATP6N1A, V-ATPase 116 kDa isoform a1, Vacuolar proton pump subunit 1, VPH1
Target Sequences: NM_005177 NP_005168.2 Q93050

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
ATP6V0A1 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
ATP6V0A1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
95.6 kDa
100 µg/$710
ATP6V0A1 Protein - 12.5% SDS-PAGE of human ATP6V0A1 stained with Coomassie Blue
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Wheat Germ Extract
GST
122.2 kDa
2 µg/$439
ATP6V0A1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ATP6V0A1 Protein - Purified recombinant protein ATP6V0A1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
95.6 kDa
20 µg/$1,107
ATP6V0A1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
95.6 kDa
20 µg/$215
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).