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Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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ATOX1
antioxidant 1 copper chaperone
ATOX1 is a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.
| Gene Name: | antioxidant 1 copper chaperone |
| Synonyms: | ATOX1, ATX1, Copper transport protein ATOX1, Metal transport protein ATX1, HAH1 |
| Target Sequences: | NM_004045 NP_004036.1 O00244 |
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