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ATF1

activating transcription factor 1

ATF1 is an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.

Gene Name: activating transcription factor 1
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: ATF1, ATF-1, EWS-ATF1, FUS/ATF-1, Protein TREB36, TREB36
Target Sequences: NM_005171 NP_005162.1 P18846

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Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
ATF1 (10)
No (10)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (3)
Myc-DDK (Flag) (2)
Human (7)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (6)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (2)
ATF1 Protein - 12.5% SDS-PAGE of human ATF1 stained with Coomassie Blue
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Wheat Germ Extract
GST
55.55 kDa
10 µg/$479; 25 µg/$670
ATF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
29.1 kDa
20 µg/$150
ATF1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ATF1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
29.1 kDa
100 µg/$494
ATF1 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
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E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.3 kDa
10 µg/$317; 50 µg/$524
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E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
30.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
ATF1 Protein - Recombinant Activating Transcription Factor 1 By SDS-PAGE
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E. coli
His-T7
29.5 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
ATF1 Protein - Recombinant Activating Transcription Factor 1 By SDS-PAGE
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E. coli
His-T7
25.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
ATF1 Protein - Recombinant Activating Transcription Factor 1 By SDS-PAGE
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E. coli
His-T7
30.0 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).