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ASXL1

additional sex combs like 1 (Drosophila)

Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator of RARA and RXRA through association with NCOA1. Acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters. Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity (By similarity). Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).

Gene Name: additional sex combs like 1 (Drosophila)
Synonyms: ASXL1, BOPS, KIAA0978, MDS
Target Sequences: Q8IXJ9 Q8IXJ9

☰ Filters
Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
ASXL1 (8)
No (8)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (2)
Select
E. coli
GST, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.6kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
ASXL1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
9.4 kDa
100 µg/$494
ASXL1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
165.3 kDa
100 µg/$710
Select
E. coli
GST, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.6 kDa
10 µg/$344; 50 µg/$584
ASXL1 Protein - 12.5% SDS-PAGE of human ASXL1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
35.9 kDa
10 µg/$479; 25 µg/$670
ASXL1 Protein - Purified recombinant protein ASXL1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
9.4 kDa
20 µg/$1,107
ASXL1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
9.4 kDa
20 µg/$150
ASXL1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
165.3 kDa
20 µg/$215
Viewing 1-8 of 8 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).