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Aspartate Aminotransferase

glutamic-oxaloacetic transaminase 1, soluble

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Gene Name: glutamic-oxaloacetic transaminase 1, soluble
Synonyms: GOT1, Aspartate Aminotransferase, ASTQTL1, Growth-inhibiting protein 18, Transaminase A, GIG18
Target Sequences: NM_002079 NP_002070.1 P17174

Publications (2)

1
CXCL14 and MCP1 are potent trophic factors associated with cell migration and angiogenesis leading to higher regenerative potential of dental pulp side population cells. Hayashi Y, Murakami M, Kawamura R, Ishizaka R, Fukuta O, Nakashima M. Stem cell research & therapy. 2015 6:111. (WB; Pig) [Full Text Article] [PubMed:26021377] [PMC:PMC4488059] Related Antibodies: LS-B24.
2
Stimulation of angiogenesis, neurogenesis and regeneration by side population cells from dental pulp. Ishizaka R, Hayashi Y, Iohara K, Sugiyama M, Murakami M, Yamamoto T, Fukuta O, Nakashima M. Biomaterials. 2013 Mar;34:1888-97. [Full Text Article] [PubMed:23245334] Related Antibodies: LS-B24.

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Antibodies (97)
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Aspartate Aminotransferase (97)
Human (58)
Mouse (67)
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Aspartate Aminotransferase Antibody - Anti-GOT2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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Aspartate Aminotransferase Sheep anti-Pig Polyclonal Antibody
Pig, Human
IF, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
Aspartate Aminotransferase Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Aspartate Aminotransferase Antibody - Anti-GOT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Aspartate Aminotransferase Goat anti-Human Polyclonal (aa157-167) Antibody
Rat, Hamster, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Aspartate Aminotransferase Antibody - Aspartate Aminotransferase antibody Western Blot of NCI-H226.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Aspartate Aminotransferase Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using GOT1 Polyclonal Antibody at dilution of 1:50.
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Aspartate Aminotransferase Antibody - Antibody (0.5 ug/ml) staining of Human Liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Aspartate Aminotransferase Goat anti-Human Polyclonal (aa22-35) Antibody
Peptide-ELISA, WB
Unconjugated
100 µg/$503
Aspartate Aminotransferase Antibody - HepG2 cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
Aspartate Aminotransferase Antibody - GOT1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (aa352-381) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (aa352-381) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (aa352-381) (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (aa352-381) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (aa352-381) (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (aa352-381) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (aa352-381) (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
Aspartate Aminotransferase Antibody - ICC/IF analysis of GOT1 in A549 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human GOT1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).ICC/IF analysis of GOT1 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human GOT1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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Aspartate Aminotransferase Mouse anti-Human Monoclonal (AT3G11) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
Aspartate Aminotransferase Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Aspartate Aminotransferase Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Aspartate Aminotransferase Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Aspartate Aminotransferase Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
100 µl/$749
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
100 µg/$749
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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Aspartate Aminotransferase Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$361
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Aspartate Aminotransferase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).