ASNA1

arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

ASNA1 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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ASNA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116720

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.6 kDa

Price:

100 µg/$494

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Human ASNA1 Protein (Recombinant His-SUMO) (Full Length) - LS-G20504

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

54.6 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human ASNA1 Protein (Recombinant GST) (Full Length) - LS-G27546

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

65.2 kDa

Price:

2 µg/$439

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Human ASNA1 Protein (Recombinant GST, N-terminus) (aa239-348) - LS-G57832

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ASNA1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67751

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.6 kDa

Price:

20 µg/$1,107

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Human ASNA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80634

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.6 kDa

Price:

20 µg/$150

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Human ASNA1 Protein (Recombinant His) - LS-G1970

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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