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ASL / Argininosuccinate Lyase

argininosuccinate lyase

ASL / Argininosuccinate Lyase encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Name: argininosuccinate lyase
Synonyms: ASL, ASAL, Argininosuccinate lyase, Argininosuccinase, Arginosuccinase
Target Sequences: NM_000048 NP_000039.2 P04424

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Products
Proteins (12)
Over-Expression Lysate (8)
Recombinant (4)
ASL / Argininosuccinate Lyase (12)
No (12)
GST (1)
His (1)
Myc-DDK (Flag) (10)
Human (8)
293T Cells (4)
E. coli (1)
HEK 293 Cells (6)
Wheat Germ Extract (1)
Purified (1)
ASL / Argininosuccinate Lyase Protein - Purified recombinant protein ASL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
51.5 kDa
20 µg/$1,107
ASL / Argininosuccinate Lyase Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
ASL / Argininosuccinate Lyase Protein - Purified recombinant protein ASL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
51.5 kDa
20 µg/$1,107
ASL / Argininosuccinate Lyase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
49.3 kDa
20 µg/$215
ASL / Argininosuccinate Lyase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
48.6 kDa
20 µg/$215
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293T Cells
Myc-DDK (Flag)
51.5 kDa
20 µg/$150
ASL / Argininosuccinate Lyase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
51.5 kDa
20 µg/$215
ASL / Argininosuccinate Lyase Protein - 12.5% SDS-PAGE of human ASL stained with Coomassie Blue
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Wheat Germ Extract
GST
76.78 kDa
10 µg/$479; 25 µg/$670
ASL / Argininosuccinate Lyase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51.5 kDa
100 µg/$710
ASL / Argininosuccinate Lyase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
49.3 kDa
100 µg/$710
ASL / Argininosuccinate Lyase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51.5 kDa
100 µg/$494
ASL / Argininosuccinate Lyase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
48.6 kDa
100 µg/$710
Viewing 1-12 of 12 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).