ASIP

agouti signaling protein

Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ASIP (5)

Publications

No (5)

Tag

6His-SUMO, N-terminus (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Cow (1)

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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ASIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118465

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.52 kDa

Price:

100 µg/$494

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Human ASIP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74378

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.52 kDa

Price:

20 µg/$150

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Cow ASIP Protein (Recombinant 6His-SUMO, N-terminus) (aa23-133) - LS-G56744

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Human ASIP Protein (Recombinant GST, N-terminus) (aa33-132) - LS-G57829

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

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Human ASIP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64867

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12 kDa

Price:

20 µg/$1,107

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