ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

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Products

ELISA Kits (2)

Type

Custom (1)

Sandwich (1)

Target

ASAH2 (2)

Reactivity

Human (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (1)

Publications

No (2)

Sample Type

Plasma (1)

Serum (1)

Tissue Homogenates (1)

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Human ASAH2 (Sandwich ELISA) ELISA Kit - LS-F25469

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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Human ASAH2 (Custom ELISA) ELISA Kit - LS-F50189

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$672

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