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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ARRB2 / Beta Arrestin 2

arrestin, beta 2

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: arrestin, beta 2
Synonyms: ARRB2, Arrestin 3, Arrestin beta-2, ARB2, ARR2, BARR2, Arrestin, beta 2, Beta-arrestin-2
Target Sequences: NM_004313 NP_004304.1 P32121

Publications (2)

1
Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys. Zakrzewicz A, Krasteva G, Wilhelm J, Dietrich H, Wilker S, Padberg W, Wygrecka M, Grau V. Immunobiology. 2011 216:854-61. [PubMed:21193245] Related Antibodies: LS-C54486.
2
Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia. Napolitano F, Pasqualetti M, Usiello A, Santini E, Pacini G, Sciamanna G, Errico F, Tassone A, Di Dato V, Martella G, Cuomo D, Fisone G, Bernardi G, Mandolesi G, Mercuri NB, Standaert DG, Pisani A. Neurobiology of disease. 2010 38:434-45. [PubMed:20227500] Related Antibodies: LS-C54486.

Filtered by: None
Target
ARRB2 / Beta Arrestin 2 (38)
Reactivity
Human (38)
Mouse (9)
Rat (10)
Bat (5)
Bovine (6)
Chimpanzee (3)
Dog (5)
Gibbon (4)
Hamster (1)
Horse (5)
Monkey (7)
Orangutan (3)
Pig (5)
Rabbit (5)
Xenopus (1)
Zebrafish (1)
Application
IHC (21)
IHC-P (11)
WB (31)
ELISA (10)
ICC (1)
IF (8)
IP (4)
Peptide-ELISA (3)
Host
rabbit (33)
mouse (1)
goat (4)
Isotype
IgG (22)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (37)
Clone
3G1 (1)
Format
APC (1)
APC Conjugated (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (24)
Epitope
aa262-430 (8)
aa151-200 (4)
aa23-40 (1)
aa264-298 (1)
aa310-360 (1)
aa351-361 (1)
aa355-405 (1)
aa395-409 (1)
internal region (1)
Publications
No (37)
Yes (1)
Showing 1-25 of 38 results

IHC-plus™ ARRB2 / Beta Arrestin 2 Antibody (clone 3G1) LS-B6008
Mouse Monoclonal [clone 3G1] (IgG2a,k) to Human ARRB2 / Beta Arrestin 2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg  $495.00
Anti-Beta-Arrestin 2 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-Beta-Arrestin 2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ ARRB2 / Beta Arrestin 2 Antibody (aa23-40) LS-B7973
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-ARRB2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Western blot of ARRB2 in HUVEC cell lysate in the 1) absence and 2) presence of immunizing peptide using ARRB2 / Beta Arrestin 2 Antibody at 0.25 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.

ARRB2 / Beta Arrestin 2 Antibody (aa351-361) LS-C54486
Publications (2)
Publications (2)
Goat Polyclonal to Human ARRB2 / Beta Arrestin 2
Human
Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
Goat Anti-Arrestin beta 2 Antibody (4µg/ml) staining of paraffin embedded Human Cerebellum. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. This data is from a previous batch, not on sale.
Antibody (0.03 ug/ml) staining of Human Spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ARRB2 / Beta Arrestin 2 Antibody LS-C502285
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA002135LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using ARRB2 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

ARRB2 / Beta Arrestin 2 Antibody LS-C664389
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg  $355.00

ARRB2 / Beta Arrestin 2 Antibody LS-C331317
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Human
IF, IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human breast cancer tissue.
Immunohistochemistry of paraffin-embedded human normal colon tissue.

ARRB2 / Beta Arrestin 2 Antibody (aa355-405) LS-C290443
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Human
IHC, IHC-P, IP, WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human Beta-Arrestin 2 by Immunohistochemistry. Samples: FFPE sections of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-Beta-Arrestin 2 used at a dilution of 1:1000. Detection: DAB.
Detection of Human Beta-Arrestin 2 by Immunohistochemistry. Samples: FFPE sections of human breast carcinoma. Antibody: Affinity purified rabbit anti-Beta-Arrestin 2used at a dilution of 1:1000 (1 ug/ml) (right). Detection: DAB.

ARRB2 / Beta Arrestin 2 Antibody (aa264-298) LS-C392912
Rabbit Polyclonal to Human ARRB2 / Beta Arrestin 2
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
200µl  $325.00
Antibody staining ARRB2 in human brain tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH 6). Samples were incubated with primary antibody (1:25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
Anti-ARRB2 Antibody (C-Term) at 1:2000 dilution + human brain lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 46 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

ARRB2 / Beta Arrestin 2 Antibody (aa395-409) LS-C312986
Rabbit Polyclonal to Human ARRB2 / Beta Arrestin 2
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µg 200µl 0.5mg/ml  $305.00
ARRB2 / Beta Arrestin 2 antibody. IHC(P): Human Intestinal Cancer Tissue.
ARRB2 / Beta Arrestin 2 antibody. IHC(P): Rat Testis Tissue.

ARRB2 / Beta Arrestin 2 Antibody LS-C667718
Rabbit Polyclonal to Human ARRB2 / Beta Arrestin 2
Human
ICC, IF, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunofluorescence Image
Western blot Image

ARRB2 / Beta Arrestin 2 Antibody LS-C806093
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

ARRB2 / Beta Arrestin 2 Antibody LS-C809702
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

ARRB2 / Beta Arrestin 2 Antibody LS-C748336
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Mouse, Rat, Human
IF, IHC
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00

ARRB2 / Beta Arrestin 2 Antibody LS-C764650
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Human
IF, IHC
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

ARRB2 / Beta Arrestin 2 Antibody (internal region, Biotin) LS-C742396
Goat Polyclonal to Human ARRB2 / Beta Arrestin 2
Mouse, Rat, Human
IHC, IP, Peptide-ELISA, WB
Biotin Conjugated
100µg 0.5mg/ml  $405.00
Biotinylated antibody (1µg/ml) staining of Human Spleen lysate (35µg protein in RIPA buffer), exactly mirroring its parental non-biotinylated product. Primary incubation was 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP blocke

ARRB2 / Beta Arrestin 2 Antibody (aa151-200) LS-C81143
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl 0.5mg/ml  $365.00
ARRB2 / Beta-Arrestin 2 antibody ARRB2(arrestin, beta 2) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ARRB2 / Beta Arrestin 2 Antibody (aa151-200, HRP) LS-C450629
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Rabbit, Dog, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
ARRB2 / Beta-Arrestin 2 antibody ARRB2(arrestin, beta 2) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ARRB2 / Beta Arrestin 2 Antibody (aa151-200, Biotin) LS-C450627
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Rabbit, Dog, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100µl 1mg/ml  $385.00
ARRB2 / Beta-Arrestin 2 antibody ARRB2(arrestin, beta 2) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ARRB2 / Beta Arrestin 2 Antibody (aa151-200, FITC) LS-C450628
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Rabbit, Dog, Bovine, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100µl 1mg/ml  $385.00
ARRB2 / Beta-Arrestin 2 antibody ARRB2(arrestin, beta 2) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ARRB2 / Beta Arrestin 2 Antibody LS-C355612
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Xenopus, Zebrafish, Rat, Hamster, Mouse, Bovine, Human, Monkey, Gibbon
IF, WB
Unconjugated
100µg  $425.00
Immunofluorescence analysis of beta-Arrestin 2 was performed using 70% confluent log phase HEK293 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with beta-Arrestin 2 Rabbit Polyclonal Antibody at 2µg/ml in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Rabbit IgG (H+L) Superclonal Secondary Antibody, Alexa Fluor® 488 conjugate at a dilution of 1:2000 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with DAPI. F-actin (Panel c: red) was stained with Rhodamine Phalloidin. Panel d represents the merged image showing cytoplasmic localization. Panel e shows the no primary antibody control. The images were captured at 60X magnification.
WB using beta-Arrestin 2 Antibody

ARRB2 / Beta Arrestin 2 Antibody LS-C192426
Rabbit Polyclonal to Human ARRB2 / Beta Arrestin 2
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl  $385.00
Western blot of ARRB2 pAb in extracts from Raw264.7 cells.

ARRB2 / Beta Arrestin 2 Antibody (aa310-360) LS-C290440
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Human
IHC, IHC-P, IP
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human Beta-Arrestin 2 by Immunohistochemistry. Samples: FFPE sections of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-Beta-Arrestin 2 used at a dilution of 1:1000 (1 ug/ml) (left). Detection: DAB.
Detection of Human Beta-Arrestin 2 by Immunohistochemistry. Samples: FFPE sections of human breast carcinoma. Antibody: Affinity purified rabbit anti-Beta-Arrestin 2 used at a dilution of 1:1000 (1 ug/ml) (left). Detection: DAB.

ARRB2 / Beta Arrestin 2 Antibody LS-C335078
Rabbit Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Human
IHC, WB
Unconjugated
100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of RAW264.7 cell line, using ARRB2 antibody.
Western blot analysis of extracts of various cell lines, using ARRB2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5s.

ARRB2 / Beta Arrestin 2 Antibody LS-C96198
Rabbit Polyclonal to Human ARRB2 / Beta Arrestin 2
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg 100µl  $345.00

ARRB2 / Beta Arrestin 2 Antibody LS-C69276
Goat Polyclonal (IgG) to Human ARRB2 / Beta Arrestin 2
Human
IHC, IHC-P
Unconjugated
100µg  $725.00
Showing 1-25 of 38 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).