ARNT2

aryl-hydrocarbon receptor nuclear translocator 2

ARNT2 is a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

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Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

ARNT2 (7)

Publications

No (7)

Tag

GST (2)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Purification

Purified (2)

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Human ARNT2 Protein (Recombinant GST) (Full Length) - LS-G31848

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

104.28 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ARNT2 Protein (Recombinant GST) (Full Length) - LS-G31849

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ARNT2 Protein (Recombinant His-T7) (aa1-209) - LS-G24761

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.7 kDa

Price:

10 µg/$269; 50 µg/$367; 100 µg/$587; 200 µg/$732; 1 mg/$1,773; 500 µg/$1,340; 5 mg/$2,729; 2 mg/$1,952

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Human ARNT2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67392

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.5 kDa

Price:

20 µg/$1,107

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Human ARNT2 Protein (Recombinant GST, N-terminus) (aa464-563) - LS-G61282

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ARNT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79731

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.5 kDa

Price:

20 µg/$215

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ARNT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101265

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.5 kDa

Price:

100 µg/$710

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