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ARHGEF18

Rho/Rac guanine nucleotide exchange factor (GEF) 18

Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. Also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS). Does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production.

Gene Name: Rho/Rac guanine nucleotide exchange factor (GEF) 18
Synonyms: ARHGEF18, p114-RhoGEF, KIAA0521, SA-RhoGEF, Septin-associated RhoGEF, p114RhoGEF, p114-RHO-GEF
Target Sequences: NM_015318 NP_056133.2 Q6ZSZ5

☰ Filters
Products
Antibodies (22)
Primary (22)
ARHGEF18 (22)
Human (22)
Dog (4)
IHC (7)
IHC-P (4)
WB (18)
ELISA (15)
ICC (1)
Peptide-ELISA (1)
rabbit (17)
mouse (4)
goat (1)
Product Group
IHCPlus (1)
IgG (16)
IgG1 (4)
monoclonal mc (4)
polyclonal pc (18)
OTI4B5 (1)
OTI6D10 (2)
OTI6G8 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
Carrier-free (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (11)
aa91-119 (7)
aa118-215 (4)
aa1160-1173 (1)
aa770-990 (1)
No (22)
ARHGEF18 Antibody - Anti-ARHGEF18 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ARHGEF18 Rabbit anti-Human Polyclonal Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ARHGEF18 Antibody - Anti-ARHGEF18 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ARHGEF18 Rabbit anti-Human Polyclonal (HRP) Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
ARHGEF18 Antibody - Anti-ARHGEF18 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ARHGEF18 Rabbit anti-Human Polyclonal (Biotin) Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
ARHGEF18 Antibody - Anti-ARHGEF18 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ARHGEF18 Rabbit anti-Human Polyclonal (FITC) Antibody
Dog, Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
ARHGEF18 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-ARHGEF18 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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ARHGEF18 Mouse anti-Human Monoclonal (aa118-215) (OTI6D10) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
ARHGEF18 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-ARHGEF18 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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ARHGEF18 Mouse anti-Human Monoclonal (aa118-215) (Carrier-free) (OTI6D10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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ARHGEF18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
ARHGEF18 Antibody - Immunofluorescence of methanol-fixed A431 using ARHGEF18 antibody at 1:200 dilution.
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ARHGEF18 Rabbit anti-Human Polyclonal (aa770-990) Antibody
Human
ICC, WB
Unconjugated
100 µl/$450
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ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ARHGEF18 Antibody - Goat Anti-P114-RHO-GEF / ARHGEF18 Antibody (0.5µg/ml) staining of lysates of cell lines Daudi (A) and Caco-2 (B) (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescencence.
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ARHGEF18 Goat anti-Human Polyclonal (aa1160-1173) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
ARHGEF18 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY ARHGEF18. (Right lane) cDNA for 48 hrs and lysed
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ARHGEF18 Mouse anti-Human Monoclonal (aa118-215) (OTI6G8) Antibody
Human
WB
Unconjugated
100 µl/$434
ARHGEF18 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY ARHGEF18. (Right lane) cDNA for 48 hrs and lysed
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ARHGEF18 Mouse anti-Human Monoclonal (aa118-215) (OTI4B5) Antibody
Human
WB
Unconjugated
100 µl/$434
ARHGEF18 Antibody - ARHGEF18 Antibody western blot of 293 cell line lysates (35 ug/lane). The ARHGEF18 antibody detected the ARHGEF18 protein (arrow).
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ARHGEF18 Rabbit anti-Human Polyclonal (aa91-119) Antibody
Human
WB
Unconjugated
400 µl/$393
ARHGEF18 Antibody - IHC image of ARHGEF18 Antibody diluted at 1:200 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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ARHGEF18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
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ARHGEF18 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ARHGEF18 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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ARHGEF18 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-22 of 22 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).