ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

ARHGEF1 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human ARHGEF1 Protein (Recombinant GST) (Full Length) - LS-G31492

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

128.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ARHGEF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67537

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.9 kDa

Price:

20 µg/$1,107

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Human ARHGEF1 Protein (Recombinant GST, N-terminus) (aa830-927) - LS-G61008

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ARHGEF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80088

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

98.6 kDa

Price:

20 µg/$150

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Human ARHGEF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80089

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.9 kDa

Price:

20 µg/$215

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ARHGEF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103484

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.9 kDa

Price:

100 µg/$710

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ARHGEF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103469

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

98.6 kDa

Price:

100 µg/$494

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