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ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.

Gene Name: Rho guanine nucleotide exchange factor (GEF) 1
Synonyms: ARHGEF1, 115-kD protein, Arp2/3 complex 34 kd subunit, GEF1, LBCL2, p115RhoGEF, LSC, Lsc homolog, SUB1.5, p115-RHOGEF
Target Sequences: NM_004706 NP_004697.2 Q92888

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Products
Antibodies (40)
Primary (40)
ARHGEF1 (40)
Human (40)
Mouse (10)
Rat (10)
Chimpanzee (3)
Gibbon (3)
IHC (4)
IHC-P (3)
WB (36)
ELISA (18)
ICC (2)
IF (7)
IP (5)
Peptide-ELISA (2)
rabbit (34)
mouse (6)
IgG (25)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (34)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (22)
aa164-192 (7)
aa230-279 (4)
140-220 aa, Internal (1)
Internal (1)
aa147-196 (1)
aa206-251 (1)
aa275-325 (1)
aa775-825 (1)
aa830-927 (1)
No (40)
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ARHGEF1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
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ARHGEF1 Mouse anti-Human Monoclonal (aa830-927) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
Select
ARHGEF1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
ARHGEF1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
Select
ARHGEF1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, WB
FITC Conjugated
100 µl/$904
Select
ARHGEF1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, WB
PE Conjugated
100 µl/$904
Select
ARHGEF1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
ARHGEF1 Antibody - ARHGEF1 was detected in paraffin-embedded sections of mouse lymphaden tissues using rabbit anti- ARHGEF1 Antigen Affinity purified polyclonal antibody
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ARHGEF1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ARHGEF1 Antibody - Immunochemical staining of human ARHGEF1 in human spleen with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections.
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ARHGEF1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P
Unconjugated
100 µl/$412
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ARHGEF1 Rabbit anti-Human Polyclonal (aa206-251) Antibody
Mouse, Rat, Human
ICC, IP, WB
Unconjugated
50 µl/$321; 100 µl/$403
ARHGEF1 Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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ARHGEF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ARHGEF1 Antibody - Immunohistochemistry of paraffin-embedded Human brain using ARHGEF1 Polyclonal Antibody at dilution of 1:50.
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ARHGEF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ARHGEF1 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using ARHGEF1 Polyclonal Antibody at dilution of 1:60.
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ARHGEF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
ARHGEF1 Rabbit anti-Human Polyclonal (aa164-192) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
ARHGEF1 Rabbit anti-Human Polyclonal (aa164-192) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
ARHGEF1 Rabbit anti-Human Polyclonal (aa164-192) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
ARHGEF1 Rabbit anti-Human Polyclonal (aa164-192) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
ARHGEF1 Rabbit anti-Human Polyclonal (aa164-192) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
ARHGEF1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
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ARHGEF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ARHGEF1 Antibody - IHC testing of FFPE mouse lymph tissue with ARHGEF1 antibody at 1ug/ml. HIER: steam sections in pH6 citrate buffer for 20 min.
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ARHGEF1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
ARHGEF1 Antibody - Western blot of RhoGEF p115 antibody
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ARHGEF1 Rabbit anti-Human Polyclonal (140-220 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
ARHGEF1 Rabbit anti-Human Polyclonal (aa275-325) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ARHGEF1 Antibody - Western blot analysis of the lysates from HepG2 cells using ARHGEF1 antibody.
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ARHGEF1 Rabbit anti-Human Polyclonal (aa147-196) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ARHGEF1 Antibody - Western blot analysis of ARHGEF1 expression in HUVEC (A); Raw264.7 (B) whole cell lysates.
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ARHGEF1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
100 µl/$299
Viewing 1-25 of 40 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).