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ARHGAP26 / GRAF

Rho GTPase activating protein 26

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Rho GTPase activating protein 26
Synonyms: ARHGAP26, GRAF, KIAA0621, GRAF1, OPHN1L, Oligophrenin-1-like protein, OPHN1L1
Target Sequences: NM_015071 NP_055886.1 Q9UNA1

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Products
Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
ARHGAP26 / GRAF (7)
No (7)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (5)
Human (5)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
ARHGAP26 / GRAF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
86 kDa
100 µg/$710
ARHGAP26 / GRAF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.1 kDa
100 µg/$710
ARHGAP26 / GRAF Protein - 12.5% SDS-PAGE of human ARHGAP26 stained with Coomassie Blue
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Wheat Germ Extract
GST
112.6 kDa
10 µg/$479; 25 µg/$670
ARHGAP26 / GRAF Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ARHGAP26 / GRAF Protein - Purified recombinant protein ARHGAP26 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
92.1 kDa
20 µg/$1,107
ARHGAP26 / GRAF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
86 kDa
20 µg/$215
ARHGAP26 / GRAF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
92.1 kDa
20 µg/$215
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).