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The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).
Gene Name: | Rho GTPase Activating Protein 23 |
Synonyms: | ARHGAP23, KIAA1501 |
Target Sequences: | AA485673 |
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