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ARFGAP3

ADP-ribosylation factor GTPase activating protein 3

ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.

Gene Name: ADP-ribosylation factor GTPase activating protein 3
Synonyms: ARFGAP3, ARF GAP 3
Target Sequences: NM_014570 NP_055385.3 Q9NP61

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
ARFGAP3 (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
ARFGAP3 Protein - Purified recombinant protein ARFGAP3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
56.7 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
56.7 kDa
20 µg/$150
ARFGAP3 Protein - 12.5% SDS-PAGE of human ARFGAP3 stained with Coomassie Blue
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Wheat Germ Extract
GST
83.4 kDa
10 µg/$479; 25 µg/$670
ARFGAP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
56.7 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).