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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ARFGAP1

ADP-ribosylation factor GTPase activating protein 1

GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine.

Gene Name: ADP-ribosylation factor GTPase activating protein 1
Synonyms: ARFGAP1, ARF GAP 1, ARF1GAP, ARF1 GAP, BA261N11.3, GAP protein, HRIHFB2281
Target Sequences: NM_018209 NP_060679.1 Q8N6T3

Publications (1)

1
Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S. Proceedings of the National Academy of Sciences of the United States of America. 2007 104:7444-8. [PubMed:17460038] [PMC:PMC1863490]

Viewing 1-25 of 57 items
ARFGAP1 Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-ARFGAP1 mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI1H4] (IgG2b) to Human ARFGAP1
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100µl   0.7mg/ml   $345.00
ARFGAP1 Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-ARFGAP1 mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI1H4] (IgG2b) to Human ARFGAP1
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
ARFGAP1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ARFGAP1 mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI1F6] (IgG2b) to Human ARFGAP1
Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100µl   0.63mg/ml   $345.00
ARFGAP1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ARFGAP1 mouse monoclonal antibody.
Select
Mouse Monoclonal [clone OTI1F6] (IgG2b) to Human ARFGAP1
Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Rabbit Polyclonal (IgG) to Human ARFGAP1
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI1H6] (IgG1) to Human ARFGAP1
Human, Monkey
Flo, IF, WB
Unconjugated
100µl   0.6mg/ml   $345.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI1H6] (IgG1) to Human ARFGAP1
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI2C6] (IgG2b) to Human ARFGAP1
Human, Monkey
Flo, IF, WB
Unconjugated
100µl   0.7mg/ml   $345.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI2C6] (IgG2b) to Human ARFGAP1
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI2C5] (IgG2b) to Human ARFGAP1
Human, Monkey
Flo, IF, WB
Unconjugated
100µl   0.53mg/ml   $345.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI2C5] (IgG2b) to Human ARFGAP1
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
Select
Rabbit Polyclonal (IgG) to Human ARFGAP1
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $405.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI 2C10] (IgG2b) to Human ARFGAP1
Human
Flo, IF, WB
Unconjugated
100µl   0.4mg/ml   $345.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI 2C10] (IgG2b) to Human ARFGAP1
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ARFGAP1 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using antibody at 1:100 dilution.
Select
Rabbit Polyclonal (IgG) to Human ARFGAP1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $285.00; 100µl   $385.00
ARFGAP1 Antibody - Western blot analysis using ARFGAP1 mouse mAb against MOLT4 (1), C2C12 (2), HepG2 (3), MCF-7 (4), and Lncap (5) cell lysate.
Select
Mouse Monoclonal [clone 1C4E2] (IgG2b) to Human ARFGAP1
Human
ELISA, Flo, WB
Unconjugated
100µl   $365.00
ARFGAP1 Antibody - Immunohistochemistry of paraffin-embedded rat brain using ARFGAP1 antibody at dilution of 1:100 (40x lens).
Select
Rabbit Polyclonal (IgG) to Human ARFGAP1
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $295.00; 200µl   $385.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI1F9] (IgG2b) to Human ARFGAP1
Human, Monkey
Flo, IF, WB
Unconjugated
100µl   0.75mg/ml   $345.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI1F9] (IgG2b) to Human ARFGAP1
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI2D5] (IgG2b) to Human ARFGAP1
Human
Flo, IF, WB
Unconjugated
100µl   0.57mg/ml   $345.00
ARFGAP1 Antibody - Anti-ARFGAP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ARFGAP1.
Select
Mouse Monoclonal [clone OTI2D5] (IgG2b) to Human ARFGAP1
Human
Flo, IF, WB
Unconjugated, Carrier-free
100µg   $395.00
ARFGAP1 Antibody - Immunohistochemistry of paraffin-embedded rat kidney tissue.
Select
Rabbit Polyclonal (IgG) to Human ARFGAP1
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
Select
Rabbit Polyclonal to Human ARFGAP1
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human ARFGAP1
Rabbit, Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
ARFGAP1 Antibody - Peptide - + Immunofluorescence analysis of MCF-7 cells, using ARFGAP1 antibody.
Select
Rabbit Polyclonal (IgG) to Human ARFGAP1
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µg   $305.00

Viewing 1-25 of 57 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).