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ARAP2 / CENTD1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency.

Gene Name:	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms:	ARAP2, Centaurin, delta 1, Cnt-d1, Centaurin-delta-1, CENTD1, KIAA0580, PARX, Protein PARX
Target Sequences:	AB011152 BAA25506.2 Q8WZ64

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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