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ARA70 / NCOA4
nuclear receptor coactivator 4
ARA70 / NCOA4 is an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.
| Gene Name: | nuclear receptor coactivator 4 |
| Synonyms: | NCOA4, 70 kDa AR-activator, ARA70, ELE1, NCoA-4, PTC3, Ret fused, RFG, RET-activating gene ELE1, Nuclear receptor coactivator 4, Ret-activating protein ELE1 |
| Target Sequences: | NM_005437 NP_005428.1 Q13772 |
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