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APPL1 / APPL

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

APPL1 / APPL has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Gene Name: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Synonyms: APPL1, Dip13-alpha, DIP13A, DIP13alpha, AKT2 interactor, KIAA1428, APPL
Target Sequences: NM_012096 NP_036228.1 Q9UKG1

☰ Filters
Antibodies (43)
Proteins (6)
Over-Expression Lysate (2)
Primary (43)
Recombinant (4)
APPL1 / APPL (49)
Human (43)
Mouse (13)
Rat (6)
Bovine (5)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (3)
Hamster (1)
Horse (1)
Monkey (4)
Pig (5)
Rabbit (1)
IHC (11)
IHC-P (5)
WB (37)
ELISA (11)
IF (1)
IP (4)
Peptide-ELISA (4)
rabbit (37)
mouse (4)
goat (2)
Product Group
IHCPlus (2)
IgG (26)
IgG1 (4)
monoclonal mc (4)
polyclonal pc (39)
OTI4B11 (2)
OTI7C3 (2)
APC (1)
APC Conjugated (2)
Biotin Conjugated (4)
Carrier-free (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (25)
aa404-673 (8)
aa467-516 (4)
90-170 aa, Internal (1)
aa1-50 (1)
aa111-160 (1)
aa145-158 (1)
aa502-681 (1)
aa659-709 (1)
aa697-709 (1)
No (49)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
APPL1 / APPL Antibody - Anti-APPL1 / APPL antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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APPL1 / APPL Rabbit anti-Human Polyclonal (aa111-160) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
APPL1 / APPL Antibody - Anti-APPL1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APPL1 / APPL Rabbit anti-Human Polyclonal (aa467-516) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
APPL1 / APPL Antibody - Anti-APPL1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APPL1 / APPL Rabbit anti-Human Polyclonal (aa467-516) (HRP) Antibody
Mouse, Guinea pig, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
APPL1 / APPL Antibody - Anti-APPL1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APPL1 / APPL Rabbit anti-Human Polyclonal (aa467-516) (Biotin) Antibody
Mouse, Guinea pig, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
APPL1 / APPL Antibody - Anti-APPL1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APPL1 / APPL Rabbit anti-Human Polyclonal (aa467-516) (FITC) Antibody
Mouse, Guinea pig, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
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APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
APPL1 / APPL Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-APPL1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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APPL1 / APPL Mouse anti-Human Monoclonal (OTI4B11) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
APPL1 / APPL Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-APPL1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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APPL1 / APPL Mouse anti-Human Monoclonal (Carrier-free) (OTI4B11) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
APPL1 / APPL Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using APPL1 Polyclonal Antibody at dilution of 1:70.
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APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
APPL1 / APPL Antibody - Staining A549 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
APPL1 / APPL Antibody
Select
APPL1 / APPL Rabbit anti-Human Polyclonal (aa502-681) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
Select
APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
APPL1 / APPL Antibody - Western blot of APPL1 antibody
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APPL1 / APPL Rabbit anti-Human Polyclonal (90-170 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
APPL1 / APPL Antibody - Western blot analysis of extracts from A549 cells, using APPL1 antibody.
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APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
APPL1 / APPL Antibody - Detection of mouse APPL1/DIP13alpha by western blot. Samples: Whole cell lysate (50 µg) from NIH 3T3 and TCMK-1 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-APPL1/DIP13alpha antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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APPL1 / APPL Rabbit anti-Human Polyclonal (aa659-709) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
APPL1 / APPL Antibody - Antibody (0.5 ug/ml) staining of 1) Rat Aortic Smooth Muscle cell lysate 2) after infection with Human APPL1 adenovirus for 48hrs. Detected by chemiluminescence.
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APPL1 / APPL Goat anti-Human Polyclonal (aa145-158) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
APPL1 / APPL Antibody - Goat Anti-APPL / DIP13alpha Antibody (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescencence.
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APPL1 / APPL Goat anti-Human Polyclonal (aa697-709) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
APPL1 / APPL Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY APPL1. (Right lane) cDNA for 48 hrs and lysed
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APPL1 / APPL Mouse anti-Human Monoclonal (OTI7C3) Antibody
Human
WB
Unconjugated
100 µl/$434
APPL1 / APPL Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY APPL1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APPL1. (1:500)
Select
APPL1 / APPL Mouse anti-Human Monoclonal (Carrier-free) (OTI7C3) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
Select
APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
APPL1 / APPL Antibody - Western blot of APPL1 / APPL antibody.
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APPL1 / APPL Rabbit anti-Human Polyclonal (aa404-673) Antibody
Human
WB
Unconjugated
100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345
APPL1 / APPL Antibody - Immunohistochemistry of paraffin-embedded human pancreatic tissue using APPL1 Antibody at dilution of 1:100
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APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
APPL1 / APPL Antibody
Select
APPL1 / APPL Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
Viewing 1-25 of 49 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).