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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Apolipoprotein A-V

Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.

Gene Name: Apolipoprotein A-V
Synonyms: APOA5, Apo-AV, APOAV, Apolipoprotein A5, Apo-A5, Apolipoprotein A-V, RAP3, ApoA-V
Target Sequences: NM_052968 NP_443200.2 Q6Q788

Publications (2)

1
An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Pennacchio LA, Olivier M, Hubacek JA, Cohen JC, Cox DR, Fruchart JC, Krauss RM, Rubin EM. Science (New York, N.Y.). 2001 294:169-73. [PubMed:11588264]
2
Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms. Treviño-Villarreal JH, Reynolds JS, Bartelt A, Langston PK, MacArthur MR, Arduini A, Tosti V, Veronese N, Bertozzi B, Brace LE, Mejia P, Trocha K, Kajitani GS, Longchamp A, Harputlugil E, Gathungu R, Bird SS, Bullock AD, Figenshau RS, Andriole GL, Thompson A, Heeren J, Ozaki CK, Kristal BS, Fontana L, Mitchell JR. JCI insight. 2018 November;3:pii: 99470. [Full Text Article] [PubMed:30385734] [PMC:PMC6238732]

Filtered by: None
Target
Apolipoprotein A-V (106)
Reactivity
Human (82)
Mouse (27)
Rat (9)
Chicken (1)
Monkey (2)
Application
IHC (11)
IHC-P (6)
WB (93)
ELISA (29)
ICC (1)
IF (6)
Peptide-ELISA (1)
Host
rabbit (37)
mouse (68)
goat (1)
Isotype
IgG (10)
IgG1 (28)
IgG1,k (14)
IgG2a,k (8)
IgG2b,k (16)
Clonality
monoclonal mc (68)
polyclonal pc (38)
Clone
1G5G9 (7)
1G5G9 (c),2G1H11G9B3 (1)
2G1H11 (1)
2G1H11, 1F1E8 (2)
4H8H8E2 (6)
C11 (8)
C6 (8)
OTI1A1 (2)
OTI1A2 (2)
OTI1B4 (2)
OTI1D1 (2)
OTI1E3 (2)
OTI1G4 (2)
OTI1H4 (2)
OTI2B11 (2)
OTI3A5 (2)
Format
APC (6)
APC Conjugated (6)
Biotin Conjugated (9)
Carrier-free (9)
Cy3 Conjugated (6)
Cy7 Conjugated (6)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (6)
Unconjugated (53)
Epitope
aa167-335 (8)
aa169-367 (8)
aa21-210 (8)
N-Terminus (3)
30-110 aa, N-terminal (1)
aa22-52 (1)
aa353-366 (1)
Publications
No (106)
Showing 1-25 of 106 results

IHC-plus™ Apolipoprotein A-V Antibody (clone 1G5G9) LS-B2261
Mouse Monoclonal [clone 1G5G9] (IgG1,k) to Human Apolipoprotein A-V
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µl  $425.00
Anti-APOA5 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Detection of Apo A5 in HepG2 cell lysate .

Apolipoprotein A-V Antibody (N-Terminus) LS-C46994
Rabbit Polyclonal to Human Apolipoprotein A-V
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg 0.5mg/ml  $315.00

IHC-plus™ Apolipoprotein A-V Antibody (clone 4H8H8E2) LS-B231
Mouse Monoclonal [clone 4H8H8E2] (IgG1,k) to Human Apolipoprotein A-V
Human
ELISA, IHC, IHC-P
Unconjugated
50µl  $425.00
Anti-APOA5 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.

Apolipoprotein A-V Antibody LS-C335159
Rabbit Monoclonal (IgG) to Human Apolipoprotein A-V
Human
IHC, WB
Unconjugated
50µl  $255.00; 100µl  $295.00; 200µl  $425.00
Immunohistochemistry of formalin-fixed paraffin-embedded (FFPE) human liver using APOA5 antibody at dilution of 1:100 (40x magnification).
Western blot analysis of extracts of Recombinant protein.

Apolipoprotein A-V Antibody (aa21-210) LS-C294029
Rabbit Polyclonal to Mouse Apolipoprotein A-V
Mouse
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $515.00
Western blot of recombinant Apolipoprotein A5 / APOA5.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Recombinant protein.

Apolipoprotein A-V Antibody (clone OTI1H4) LS-C338367
Mouse Monoclonal [clone OTI1H4] (IgG1) to Human Apolipoprotein A-V
Mouse, Human, Monkey
WB
Unconjugated
100µl 1mg/ml  $345.00
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5.
Western blot of extracts (35ug) from 9 different cell lines by using anti-APOA5 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Apolipoprotein A-V Antibody (clone 2G1H11) LS-C41368
Mouse Monoclonal [clone 2G1H11] (IgG1) to Human Apolipoprotein A-V
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100µl  $475.00
Western blot using Apoa5 mouse monoclonal antibody against human serum (A) and Apoa5 recombinant protein (B).

Apolipoprotein A-V Antibody (clone OTI1A1) LS-C338386
Mouse Monoclonal [clone OTI1A1] (IgG1) to Human Apolipoprotein A-V
Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-APOA5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Human liver tissue using anti-APOA5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Apolipoprotein A-V Antibody (clone OTI1A1, Carrier-free) LS-C788470
Mouse Monoclonal [clone OTI1A1] (IgG1) to Human Apolipoprotein A-V
Human
IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-APOA5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Human liver tissue using anti-APOA5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Apolipoprotein A-V Antibody LS-C802227
Mouse Monoclonal (IgG1) to Human Apolipoprotein A-V
Human
ELISA, ICC, WB
Unconjugated
50µl 1mg/ml  $315.00; 100µl 1mg/ml  $375.00; 200µl 1mg/ml  $435.00

Apolipoprotein A-V Antibody LS-C674225
Rabbit Polyclonal (IgG) to Human Apolipoprotein A-V
Human
ELISA, IHC, IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human liver cancer at a dilution of 1:100

Apolipoprotein A-V Antibody (clone 2G1H11, 1F1E8) LS-C758487
Mouse Monoclonal [clone 2G1H11, 1F1E8] (IgG1) to Human Apolipoprotein A-V
Human
IF, WB
Unconjugated
100µl  $405.00
Apolipoprotein A5 Antibody in Western Blot (WB)

Apolipoprotein A-V Antibody (clone OTI2B11, Carrier-free) LS-C788451
Mouse Monoclonal [clone OTI2B11] (IgG1) to Human Apolipoprotein A-V
Human
IF, WB
Unconjugated, Carrier-free
100µg  $395.00
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5.

Apolipoprotein A-V Antibody (clone OTI1E3, Carrier-free) LS-C788447
Mouse Monoclonal [clone OTI1E3] (IgG1) to Human Apolipoprotein A-V
Human
IF, WB
Unconjugated, Carrier-free
100µg  $395.00
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5.

Apolipoprotein A-V Antibody (clone OTI1D1) LS-C338398
Mouse Monoclonal [clone OTI1D1] (IgG1) to Human Apolipoprotein A-V
Human
IF, WB
Unconjugated
100µl 1mg/ml  $345.00
Anti-APOA5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY APOA5.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5.

Apolipoprotein A-V Antibody (clone OTI1D1, Carrier-free) LS-C788487
Mouse Monoclonal [clone OTI1D1] (IgG1) to Human Apolipoprotein A-V
Human
IF, WB
Unconjugated, Carrier-free
100µg  $395.00
Anti-APOA5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY APOA5.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY APOA5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APOA5.

Apolipoprotein A-V Antibody (aa22-52) LS-C100609
Rabbit Polyclonal to Human Apolipoprotein A-V
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with APOA5 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of anti-APOA5 Antibody in HL60 cell line lysates (35 ug/lane). APOA5(arrow) was detected using the purified antibody.

Apolipoprotein A-V Antibody (N-Terminus) LS-C347608
Rabbit Polyclonal (IgG) to Human Apolipoprotein A-V
Human
IHC, WB
Unconjugated
100µl  $405.00

Apolipoprotein A-V Antibody LS-C405880
Rabbit Polyclonal (IgG) to Human Apolipoprotein A-V
Human
ELISA, IHC
Unconjugated
20µl 0.5mg/ml  $205.00; 60µl 0.5mg/ml  $235.00; 120µl 0.5mg/ml  $295.00; 200µl 0.5mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human liver cancer using APOA5 Polyclonal Antibody at dilution of 1:15.

Apolipoprotein A-V Antibody LS-C802195
Mouse Monoclonal (IgG1) to Human Apolipoprotein A-V
Human
ELISA, WB
Unconjugated
50µl 1mg/ml  $315.00; 100µl 1mg/ml  $375.00; 200µl 1mg/ml  $435.00

Apolipoprotein A-V Antibody LS-C69141
Mouse Monoclonal (IgG1,k) to Human Apolipoprotein A-V
Human
ELISA, WB
Unconjugated
100µl  $515.00

Apolipoprotein A-V Antibody LS-C69144
Mouse Monoclonal (IgG1,k) to Human Apolipoprotein A-V
Human
ELISA, WB
Unconjugated
100µl  $515.00

Apolipoprotein A-V Antibody LS-C126830
Mouse Monoclonal (IgG1) to Human Apolipoprotein A-V
Human
ELISA, WB
Unconjugated
100µg  $605.00

Apolipoprotein A-V Antibody LS-C126831
Mouse Monoclonal (IgG1) to Human Apolipoprotein A-V
Human
ELISA, WB
Unconjugated
100µg  $575.00

Apolipoprotein A-V Antibody (clone 4H8H8E2) LS-C84790
Mouse Monoclonal [clone 4H8H8E2] (IgG1) to Human Apolipoprotein A-V
Human
ELISA, WB
Unconjugated
100µl  $560.00
Showing 1-25 of 106 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).