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APOL3 / Apolipoprotein L 3

apolipoprotein L, 3

APOL3 / Apolipoprotein L 3 is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 22. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants.

Gene Name: apolipoprotein L, 3
Synonyms: APOL3, ApoL-III, Apolipoprotein L3, APOLIII, CG12_1, CG12-1, CG121, TNF-inducible protein CG12-1, Apolipoprotein L, 3, Apolipoprotein L-III
Target Sequences: NM_014349 NP_055164.1 O95236

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).